Preparation of Dextran-Based Macromolecular Chelates for Magnetic Resonance Angiography

MARIA G. DUARTE, CARLOS F.G.C. GERALDES, JOOP A. PETERS and MARIA H.GIL  

Abstract The preparation of macromolecular conjugates of dextran, which could be 

In the last decade there has been great interest in the development of macromolecular contrast agents to be used in Magnetic Resonance Imaging (MRI), a new diagnostic technique which provides a better contrast resolution of the tissues than others techniques, such as X-ray, ultrasound and scintigraphy. 

Low molecular weight chelates of the paramagnetic ion Gd, such as Gd-DTPA or Gd-DOTA, are generally used in MRI as contrast agents due to 

Biorelated Polymers Sustainable Polymer Science and Technology 

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Preparation of Dextran-Based Macromolecular Chelates for Magnetic Resonance Angiography... 

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