Pregnancy thyroid abnormalities

J. Kinthaert, C. Robijn, J.P. Grun and P. De Nayer, Pregnancy in patients with mild thyroid abnormalities maternal and neonatal repercussions, J Clin Endocrinol Metab. 73 421 (1991). 

Baseline tests CBC, hepatic function, pregnancy test, TSH, renal function, uric acid, HCVRNA level. Exclusions to treatment platelet count <90,000 cells/mm (as low as 75,000 cells/mm in patients with cirrhosis) absolute neutrophil count < 1,500 cells/mm serum creatinine concentration > 1.5 X upperlimit of normal abnormal thyroid function... 

Ultrasound has superseded amniofetography, a procedure in which contrast media are injected into the amniotic sac during pregnancy to delineate fetal abnormalities. Diatrizoate, iotalamate, and, earher, iodized oil were used. There is a theoretical risk of premature labor. Accidental injection of contrast medium into the fetal subcutaneous tissues could cause sloughing of the skin or subcutaneous necrosis. Cases of thyroid hjrperplasia or hypothyroidism were also commonly described. 

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