Pregnancy cystitis

Clinical use is generally for the termination of pregnancy, but it is also used in postpartum hemorrhage. Following administration to the bladder, it has also proved useful in cyclophosphamide-induced hemorrhagic cystitis in bone marrow patients (342). 

Acute cystitis occurs in 0.3% to 1.3% of pregnancies. In addition to having significant amounts of bacteria in the urine, women with acute cystitis complain of urinary frequency and pain." The risks of low birth weight and preterm labor associated with acute cystitis have not been defined. Treatment for acute cystitis is the same as described for asymptomatic bacteriuria." ... 

Infection of the genitourinary tract, an important target in ruminant animals, also may lead to signs and symptoms of disease in man.39,40 Pyelonephritis and cystitis and, in males, epididymoorchitis, may occur. Both diseases may mimic their tuberculous counterparts, with sterile pyuria on routine bacteriologic culture. With bladder and kidney infection, Brucella organisms can be cultured from the urine. Brucellosis in pregnancy can lead to placental and fetal infection.41 Whether abortion is more common in brucellosis than in other severe bacterial infections, however, is unknown. 

A 38-year-old woman was seen as an emergency patient in the clinic. She reported fever, chills, and pain in her back, as well as urinary frequency. This had developed over the previous 24 hours. She did not recall any previous incidents that were similar. Her past history was positive for multiple incidents of cystitis as a child and occasional bouts of dysuria and frequency of urination over the past 3 to 4 years. She had seen her physician for these and was placed on antibiotics for relief. She often medicated herself for these symptoms. She had no other major illnesses or surgery and had two pregnancies that were uneventful. She stated that her menstrual cycles were regular and that she did not take oral contraceptives. 

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