Pregnancy-associated plasma protein

Pregnancy Associated Plasma Protein A Pregnancy associated plasma protein A (PAPP-A) is a metalloproteinase expressed when IGF is freed from inhibition. It is drought to be expressed in plaques that may be prone to rupture. The literature in this regard is mixed at present concerning its At present, there is no standardized... 

Bayes-Genis A, Conover CA, Overgaard MT, Bailey KR, Christiansen M, Hohnes DR Jr. et al. Pregnancy-associated plasma protein A as a marker of acute coronary syndromes. N Engl J Med 2001 345 ... 

Lund J, Qin QP, Ilva T> Pettersson K, Voipio-Pulkki LM, Porela P, et al. Circulating pregnancy-associated plasma protein A predicts outcome in patients with acute coronary syndrome but no troponin I elevation. Circulation 2003 108 1924-6. 

Qin QP, Laitinen P, Majamaa-Voltti K, Release patterns of pregnancy associated plasma protein A (PAPP-A) in patients with acute coronary syndromes. Scand Cardiovas J 2002 36 358-61. 

Figure 54-1 Schematic representation of steroid and protein hormone production by the placenta. DHEA-S, Dehydro-epiandrosterone sulfate CG, chorionic gonadotropin PL, placental lactogen ACTH, adrenocorticotropic hormone TRH, thyroid-stimulating hormone CT, chorionic thyrotropin GnRH, gonadotropin-releasing hormone CRH, corticotropin-releasing hormone PAPP-A, pregnancy associated plasma protein-A.

Forest JC, Masse J, Moutquin JM. Screening for Down syndrome during first trimester a prospective study using free beta-human chorionic gonadotropin and pregnancy-associated plasma protein A. Cfin Biochem 1997 30 333-8. 

Lin, T.M., Halbert, S.P., and Kiefer, D., 1976, Quantitative analysis of pregnancy-associated plasma proteins inhuman placenta. J. Clin. Invest. 57 466-472. 

L., and Oxvig, C., 2003, Complex of Pregnancy-associated Plasma Protein-A and the Proform of Eosinophil Major Basic Protein. J. Biol. Chem. 278 2106-2117. 

Page, N.M., Butlin, D.J., Lomthaisong, K., and Lowry, P.J., 2001, The characterization of pregnancy associated plasma protein-E and the identification of an alternative sphce variant. Placenta. 22 681-687. 

Qin Q, Christiansen M, Lovgren T, Norgaard-Pedersen B, Pettersson K (1997) Dual-label time-resolved immunofluorometric assay for simultaneous determination of pregnancy-associated plasma protein A and free beta-subunit of human chorionic gonadotropin. J Immunol Methods 205 169-175... 

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