Pregnancy alpha-fetoprotein

C. B. Reimer, S. J. Smith, and T. W. Wells, The U.S. National Reference Preparation for Alpha-Fetoprotein in Mid-Pregnancy Maternal Serum. Clin. Chem. 28 709-716 (1982). 

Figure 54-5 Distribution of maternal serum alpha fetoprotein (AFP) measurements in unaffected pregnancies, and pregnancies affected with open spina bifida or anencephaly.

Figure 54-12 Concentrations of alpha fetoprotein (AFP) in fetal and newborn serum, maternal serum, and amniotic fluid. The maternal serum values are medians calculated from 24,232 pregnancies and the amniotic fluid values are medians calculated from 1544 pregnancies from testing performed at ARUP Laboratories Inc. from January to October 1997.The fetal serum values are from Gitlan. The newborn serum values are from Wu et aU "...

A. Cuckle HS, Wald NJ, Thompson SG. Estimating a woman s risk of having a pregnancy associated with Down s syndrome using her age and serum alpha-fetoprotein level. Br J Obstet Gynaecol 1987 94 387-402. 

Wald NJ, Cuckle H, Brock JH, Peto R, Polani PE, Woodford FP. Maternal serum-alpha-fetoprotein measurement in antenatal screening for anencephaly and spina bifida in early pregnancy. Report of U.K. collaborative study on alpha-fetoprotein in relation to neural-tube defects. Lancet 1977 1(8026) 1323-32. 

Wald NJ, Hacksliaw A, Stone R, Densem J. Serum alpha-fetoprotein and neural tube defects in the first trimester of pregnancy. MRC Vitamin Study Research Group. Prenat Diagn 1993 13 1047-50. 

Wathen NC, Campbell DJ, Kitau MJ, Chard T. Alpha-fetoprotein levels in amniotic fluid from 8 to 18 weeks of pregnancy. Br J Obstet Gynaecol 1993 100 380-2. 

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