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Pre-clinical drug discovery and development

NIH Translational Programs for Assisting Pre-Clinical Drug Discovery and Development... [Pg.363]

The pre-clinical drug development process has as its end product a drug candidate that is suitable for testing in human clinical trials. To achieve this, the candidate must pass pre-clinical toxicology testing, have its adsorption, distribution, metabolism and excretion understood in suitable animal models, and have good scientific evidence that it will provide medicinally beneficial effects. The latter normally requires showing efficacy in animal models of the disease. The early phase discovery process has usually... [Pg.61]

Bostrom, J. (2013) Not Even Wrong -The Failure of Drug-likeness Rules. http //www.pharma-iq.com/pre-clinical-discovery-and-development/articles/not-even-wrong-the-lailure-of-drug-likeness-rules/ (accessed 7 September 2015). [Pg.125]

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See also in sourсe #XX -- [ Pg.361 , Pg.362 , Pg.363 , Pg.364 , Pg.365 , Pg.366 , Pg.367 , Pg.368 , Pg.369 , Pg.370 , Pg.371 , Pg.372 , Pg.373 , Pg.374 , Pg.375 ]



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Drug discovery and development

Pre-Clinical Developments

Pre-clinical

Pre-clinical drug discovery and

Pre-drugs

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