Potential disease-associated gene products

Gene therapy, which involves insertion and expression of a therapeutic gene into cells followed by production of the required proteins, emerged as a new paradigm in medicine with enormous therapeutic potential. In 2000, gene therapy research came into the picture by successful treatment of a genetic disease called X-linked severe combined immunodeficiency. However, adverse events such as T cell leukemia, which developed in some patients in clinical trials, raised many questions regarding associated risks. 

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