Post-exposure prophylactic therapies

Exposure of skin to chemical warfare agents can be reduced by the use of barrier creams, decontaminants or by removal of superficially absorbed chemicals ( catch-up therapies ). In short, prophylactic barrier creams seek to prevent skin contact whereas decontaminants and catch-up therapies are post-exposure measures that can only minimise skin absorption. Barrier creams may also be applied to skin under PPE to enhance protection at vulnerable areas, such as the groin and axillae. 

Conventionally, NA poisoning is treated by a combi-nahon of prophylactic and post-exposure therapy, which target the three post-exposure phases of neurotransmitter systems described. Prophylactic treatments are designed to circumvent aging of e NA-AChE complex and consist of carbamate anticholinesterases (e.g., pyridostigmine)... 

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