Positron emission transaxial

Aryltriazenes can also be decomposed by hydrogen fluoride in organic solution after extraction from their aqueous mother phase. In this case, hydrogen fluoride can be used in small excess but the nature of the solvent is crucial for example, tetrahydrofuran gives complex mixtures, dichloromethane promotes radical reactions (dimerizations, reductions) and acetic acid favors triazene decomposition before fluorination. Aromatic and haloaromatic compounds seem to be the best solvents.283 Such a technique, especially suited for the rapid introduction of an 18F atom, has been employed to produce [ 8F]haloperidol (3), the specific receptors of which have been localized in the brain by positron emission transaxial tomography.298... 

Positron-emission, transaxial tomography (PETT) is a recent extension of these visualization techniques/12 and a study of a 19F derivative of phenazocine (Jluorophen) has been made with a view to employing the 18F congener, the form required for a PETT scan/13 ... 

Positron emission transaxial tomography (PET) Technique used to measure activity in selected brain regions (C hapter 3). 

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