Pontomesencephalic tegmentum

Webster, HH and Jones, BE (1988) Neurotoxic lesions of the dorsalateral pontomesencephalic tegmentum-cholinergic cell area in the rat. II Effects upon sleep-waking states. Brain Res. 458 285-302. 

Maloney, K. J., Mainvilie, L. Jones, B. E. (1999). Differential c-Fos expression in cholinergic, monoaminergic, and GABAergic cell groups of the pontomesencephalic tegmentum after paradoxical sleep deprivation and recovery. J. Neurosci 19, 3057-72. 

Ford, B., Holmes, C. J., Mainville, L. Jones, B. E. (1995). GABAergic neurons in the rat pontomesencephalic tegmentum codistribution with cholinergic and other tegmental neurons projecting to the posterior lateral hypothalamus. J. Comp. Neurol. 363, 177-96. 

LC consists mostly of NE neurons. However, y-aminobutyric acid (GABA)-secreting neurons are also found in the peripheries of the LC (Iijima and Ohtomo 1988). The NE neurons of LC have local and distant afferent and efferent connections. The local bilateral connections of LC arrive from and project to the GABA cells of periaqueductal gray (PAG) and acetylcholine (ACH) neurons of pontomesencephalic tegmentum (PMT) (Jones, 1991). 

Morilak DA, Ciaranello RD. 5-HT2 receptor immunoreactivity on cholinergic neurons of the pontomesencephalic tegmentum shown by double immunofluorescence. Brain Res 1993 627 49-54. 

Woolf NJ, Butcher LL (1989) Cholinergic systems in the rat brain IV. Descending projections of the pontomesencephalic tegmentum. Brain Res. Bull, 23, 519-540. 

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