POMONA

Mediciaal Chemistry Project at Pomona College National Engineering Laboratory (NEL, U.K.)... 

Ernest Simpson, California State Polytechnic University- Pomona... 

Hansch C, Leo AJ. 1985. MedChem Project. Issue No. 26, Claremont, CA Pomona College. 

Department of Chemistry, Pomona College, 645 North College Avenue,... 

The E-state indices may define chemical spaces that are relevant in similarity/ diversity search in chemical databases. This similarity search is based on atom-type E-state indices computed for the query molecule [55]. Each E-state index is converted to a z score, Z =(% -p )/0 , where is the ith E-state atomic index, p is its mean and O is its standard deviation in the entire database. The similarity was computed with the EucHdean distance and with the cosine index and the database used was the Pomona MedChem database, which contains 21000 chemicals. Tests performed for the antiinflamatory drug prednisone and the antimalarial dmg mefloquine as query molecules demonstrated that the chemicals space defined by E-state indices is efficient in identifying similar compounds from drug and drug-tike databases. 

Leo, A. J. The MedChem Database, BioByte Corp. and Pomona College, Daylight Chemical Information Systems, Mission Viejo, CA, 2003. 

Hematology-Oncology Medical Group of Orange County, Inc. Pomona, California... 

Physicochemical Parameter Database, Medicinal Chemisry Project, Pomona College, Claremont, CA, USA (www.biobyte. com/bb/pr od/cqsar. html). 

There are several people I would like to thank regarding the creation of this book. The library staff at JFK Medical Center in Edison, New Jersey and Richard Stockton College in Pomona, NJ has been indispensable with their assistance in research. The editors and staff at MTT Press have also been extremely helpful in guiding me through the process of publishing a book. 

Computer Graphics Laboratory, University of California, San Francisco, CA 94143 Department of Chemistry, Pomona College, Claremont, CA 91711... 

We wish to thank Dr. David Weininger and Dr. Albert Leo at the MedChem Project, Department of Chemistry, Pomona College for providing us with the SMILES software. 

FIGURE 4-22 Number of days in 1973 on which the maximal hourly average oxidant concentration equaled or exceeded 0.20 ppm at six air monitoring stations in the southern California coast air basin. Data as reported Los Angeles, Pasadena, Pomona, and Azusa reported by Los Angeles County apcd Riverside reported by Riverside County apcd and San Bernardino reported by San Bernardino County APCD. Reprinted with permission from Ktts. ... 

LOS ANGELES PASADENA 0 POMONA AZUSA 0 RIVERSIDE 0 SAN BERNARDINO... 

ARB METHOD (LOS ANGELES DOWNTOWN. RASA- VOENA. AZUSA. POMONA DATA 7/5 )... 

Hansch. C. and Leo. A. Pomona College Medicinal Chemistry Project Claremont, CA Pomona College, Jnly 1987). Hansch. C.. Leo. A., and Hoekman, D. Exploring QSAR hydrophobic, electronic and steric effects (Washington, DC American Chemical Society. 1995). 

The examples from SciFinder and the Merck Index are not intended to question the quality of these products, which we consider to be outstanding. They are invaluable resources to many chemists worldwide, and the error rate in these two databases is insignificant if one takes into account the enormous volume of indexed data. One of us has published a structure-activity paper on HIV-protease inhibitors [31] where a modified peptide was present in both the training set and the test set. Al Leo of Pomona College has recently [32] detected 100 chemical and name errors in the printed version of the sixth edition of Burger s Medicinal Chemistry [33], errors that will be corrected in the on-line edition [34]. One can never be too careful in verifying the available information, in particular if one is to invest a significant amount of resources in that area. 

Manual" Medicinal Chemistry Project, Pomona College, Claremont, 1984. 

In the search for more effective post-emergent herbicides, many laboratories have measured the inhibition of photosystem II in chloroplasts i.e., the Hill reaction. In a continuing investigation of this system, ( ) Corwin Hansch s group at Pomona College, in cooperation with BASF in Germany, analyzed two sets of phenyl substituted ureas 17 1,1-dimethyl-3-phenyl, and 38... 

Hansch C, LeoAJ. 1985. Medchem Project. Claremont, CA Pomona College,Issue 26. 

Prior, R.L., Absorption and metabolism of anthocyanins potential health effects. Phytochemicals Mechanisms of Action, 4th International Phytochemical Conference, Phytochemicals Mechanisms of Action , Pomona, CA (October 21-22, 2002), 2004. 

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