Polymerizable hydrogels

Piirma I. Polyelectrolytes, polyampholytes, hydrogels, and polymerizable surfactants. In Polymeric Surfactants, Surfactant Science Series. Vol. 42, New York Marcel Dekker, 1992 225-265. 

Piperidines ( NH, 2 NR, NOH, NOR) bearing polymerizable vinylic or glycidyl moieties, e.g. 182, 183 were proposed for free-radical homo- and copolymerization or grafting of conventional polymers. HAS-functionalized copolymers have a potentially important application in stabilization of hydrogels [285]. Monomer 184 is a crosslinking agent in acrylate hydrogels [286],... 

Bacterial exotoxins, poly(methacrylic acid) hydrogels as carriers, 288-295 Bioactive chemicals, polymerizable, use for surface biolization, 66-74 Bioadhesion, definition, 45 Biocompatibility bioadhesive siufaces,45-48 definition, 37 groups, 37,38/... 

FIGURE 2.3.1 An example of polymerization systems dextran carrying polymerizable methacrylate groups via biodegradable linkers can be polymerized to form biodegradable hydrogels. Reprinted with permission from Ref. [17]. 

The use of polymerizahle surfactants (surface-active macromer, SAM) in sihcone formulations has been explored to form hydrogel-like surfaces without a surface treatment (124). Several surface-active water-soluble macromers were evaluated. The SAMs were prepared using a two-step S5mthetic procedime. In this procedure, hydrophobic alkylmethacrylates or fluoromethacrylates monomers are pol5unerized with polyoxyethylene methacrylates using afunctional mercaptan as a chain-transfer agent. The resultant hydroxyl or carboxylate capped macromer (22) is further fimctionalized with a polymerizable methacrylate. 

Lu, Z. R., Kopeckova, P. and Kopecek, J. (2003). Antigen responsive hydrogels based on polymerizable antibody Fab fragment. Macromolecular Bioscience, 3,296-300. 

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