Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Polyketide synthases enediyne

The biosynthesis of maduropeptin has not been studied in detail, but an iterative type I polyketide synthase gene predicted to be responsible for forming the enediyne core structure has been identified [188]. [Pg.433]

Liu, W., Ahlert, J., Gao, Q. et al. (2003) Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model. Proceedings of the National Academy of Sciences of the United States of America, 100, 11959. [Pg.258]

Polyketide Biosynthesis, Enediyne Polyketides Polyketide Biosynthesis, Aromatic Polyetides Polyketide Biosynthesis, Modular Polyketide Synthases Polyketide Biosynthesis, Polyethers Polyketides as Drugs... [Pg.1522]

The biosynthesis of the enediyne core of calicheamicin and other similar compounds (both nine- and ten-membered) involve a common enediyne polyketide synthase (named PKSE) [295,... [Pg.302]

Figure 1. Naturally occurring enediynes and natural products for which enediynes have been proposed as biosynthetic intermediates, (a) The 10-memberedfamily includes calicheamicin, dynemicin, esperamicin, shishijimicin, namenamicin, and uncialamycin. (b) The 9-membered enediynes include neocarzinostatin (NCS), C-1027, maduropeptin, kedarcidin, andN1999A2. (c) Sporolides A and B and cyanosporasides A and B are all hypothesized to originate from enediyne precursors (bracketed) based on the presence of the enediyne polyketide synthase (PKSE) in the Salinaspora genome of each producing organism. Figure 1. Naturally occurring enediynes and natural products for which enediynes have been proposed as biosynthetic intermediates, (a) The 10-memberedfamily includes calicheamicin, dynemicin, esperamicin, shishijimicin, namenamicin, and uncialamycin. (b) The 9-membered enediynes include neocarzinostatin (NCS), C-1027, maduropeptin, kedarcidin, andN1999A2. (c) Sporolides A and B and cyanosporasides A and B are all hypothesized to originate from enediyne precursors (bracketed) based on the presence of the enediyne polyketide synthase (PKSE) in the Salinaspora genome of each producing organism.
The Enediyne Polyketide Synthase (PKSE) Evolutionary Origins and a Means by Which to Find New Bioactive... [Pg.209]

See other pages where Polyketide synthases enediyne is mentioned: [Pg.426]    [Pg.247]    [Pg.305]    [Pg.167]    [Pg.154]    [Pg.155]    [Pg.77]    [Pg.990]    [Pg.4188]    [Pg.209]    [Pg.210]    [Pg.36]   


SEARCH



Enediyne

Polyketide

Polyketide synthase

Polyketide synthases

Polyketides

© 2024 chempedia.info