Poly-s-caprolactones

Lei et al 3D polycaprolactone-20% tricalcium phosphate composites In vitro degradation and Von Kossa assays 

Lefevre et al Polycaprolactone films Biodegradation by pure strain of microorganisms isolated from an industrial composting unit 

Kunioka et al PCL powders Controlled composting medium at 58 °C using the microbial oxidative degradation analyzer based on ISO 14855-2 

Kulkarni et Multi-block copol5mers consisting of PCL segments and poly(p-dioxanone) segments Hydrolytic and Pseudomonas lipase catalysed enzymatic degradation 

Deng et al Water-resistant composite plastics prepared from soy protein isolate, PCL and toluene-2,4-diisocyanate as compatibilizer Burial in two series of sheets in soil and culturing in a mineral salt medium containing microorganisms 

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Poly(s-Caprolactone) Copolymers with Glycolide or Lactide.228... 

Although the biocompatibility and biodegradability of these materials were rapidly determined, the bioactivity of Si02-PCL hybrid materials was not studied until recently [99]. In order to provide bioactivity to Si02-PCL hybrid materials, Rhee prepared triethoxysilane end-capped poly(s-caprolactone) which was then cocondensed with tetraethyl orthosilicate and calcium nitrate via the sol-gel method. The Ca-containing PCL/silica hybrid so obtained showed in vitro bioactivity and biodegradability. The hybridization procedure between the a,co-hydroxyl PCL and silica phases was proposed to be as follows ... 

Lang M, Wong RP, Chu C-C (2002) Synthesis and structural analysis of functionalized poly (s-caprolactone)-based three arm star polymers. J Polym Sci A Polym Chem 40 1127-1141... 

A reaction vessel was charged with the step 2 product, poly (s-caprolactone), poly-(caprolactone) diol (100 g), and antimony trioxide (0.2 g) heated to 100°C for 30 minutes and the temperature gradually increased to 160°C under a very high vacuum for... 

Ge, H., Y. Hu, X. Jiang, D. Cheng, Y. Yuan, H. Bi, and C. Yang. 2002. Preparation, characterization, and drug release behaviors of drug nimodipine-loaded poly(s-caprolactone)-poly(ethyleneoxide)-poly(e-caprolactone) amphiphilic triblock copolymer micelldsPharm. Sci91 1463-1473. 

Poly(s-caprolactone) Poly(e-caprolactone) is a semicrystalline polymer synthesized by anionic, cationic, free-radical, or ring-opening polymerization [94]. It is available in a range of molecular weights and degrades by bulk hydrolysis autocatalyzed by the carboxylic acid end groups. The presence of enzymes such as protease, amylase, and pancreatic lipase accelerates polymer degradation [95], The various methods of preparation of poly(e-caprolactone) nanoparticles include emulsion polymerization, interfacial deposition, emulsion-solvent evaporation, desolvation, and dialysis. These methods and various applications are extensively reviewed [94],... 

A mixture consisting of poly(s-caprolactone-co-trimethylene carbonate) (0.129 mmol), the Step 3 product (1.79 mmol), pyridine (0.62 mmol), and 20.5 ml of CH2CI2 were stirred overnight at ambient temperature. The end-capped polymer was precipitated in diethyl ether and then purified by fractionation using DMF and diethyl ether/methanol, 8 2 the product was isolated in 86% yield. 

M Poly(s-Caprolactone-co-Trimethylene Carbonate) (daltons) OH value (mol/g) M of Post UV Cured End-Capped Poly(E-Caprolactone-co-Trimethylene Carbonate) Coumarin Ester (daltons)... 

Crosslinkable monomers A-[3-(7-methyl-9-oxothioxanthene-3-carboxamido)-propyl]methacrylamide, (I), and poly(s-caprolactone-co-trimethylene carbonate) (II), were prepared by Chudzik [4] and used in UV photo-crosslinkable implants. 

Two trifunctional benzophenone derivatives have been synthesized that are UV photoactive at 254 nm and photolytically incorporated into poly(s-caprolactone) and poly(vinylpyrrolidone). These agents are designed to be used in photopolymerization... 

Poly-s-caprolactone (—O—(CH2)4—CO—) , PCL, is a crystalline polymer of density 1.1 g/coT. When a sample of molecular weight M — 50,000 g/mol is blended with amorphous poly(vinyl phenol), PVPH, of molecular weight 1500 g/mol and density 1.2 g/cm, homogeneous mixtures are formed. The table below gives the values determined for the melting point of PCL as a function of the volume fraction poly(vinyl phenol), v. ... 

Wauthier, H. Process for the Manufacture of Poly(s-caprolactones) and Poly(s-caprolactones) Which Have High Molecular Masses Obtainable by this Process U.S. Patent No. 5,468,837, Nov 21, 1995. 

The electrospinning of poly(s-caprolactone) (PCL) solutions have been reported by Reneker et al. [74]. They varied the PCL solution concentrations between 14 and 18 wt%. The instability in the electrospinning of PCL results in the contact and merging of segments in different loops of the electrospinning jet to form garlandlike fibrous structures [74]. Yoshimoto et al. [75] have studied the potential of electrospun PCL fiber mats for use in bone tissue engineering. They found that the... 

Kim and White (2004) Polymerization of poly- s-caprolactone Engineering model linking residence-time-model, shear-effects model and reaction conversion during extrusion Reaction conversion and from extruder via correlating specific mechanical energy and Mw... 

Scheme 1 Three-step synthesis ofpoly[2-(N,N-dimethylamino)ethyl methacrylate-l-poly(s-caprolactone)] conetworks (PDMAEMA-l-PCL)...

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