Poly -grafted polysaccharides

Maruyama, A, Ishihara, T., Kim, J.S., Kim, S.W. and Akaike, T. (1997) Nanoparticle DNA carrier with poly(L-lysine) grafted polysaccharide copolymer and poly(D,L-lactic acid). Bioconjug. Chem., 8, 735-742. 

Y. Ohya, S. Maruhashi, T. Hirano, and T. Ouchi, Preparation of poly (lactic acid)-grafted polysaccharides as biodegradable amphiphilic materials, in Biomedical Polymers and Polymer Therapeutics, pp. 139-148, 2002. 

PREPARATION OF POLY(LACTIC ACID)-GRAFTED POLYSACCHARIDES AS BIODEGRADABLE AMPHIPHILIC MATERIALS... 

Preparation of Poly (lactic acid)-Grafted Polysaccharides... 

General Trend Polysaccharide-graft-poly(hydroxyalkanoate)s... 

In this review, we addressed the synthesis of well-defined monodimensional sugar-grafted polysiloxanes. For this reason, we excluded from this paper the synthesis of silicones (poly)-glycosides as surfactants, obtained by glycosylation of hydroxyl-terminated polysiloxanes and the preparation of polysaccharide-silicone adducts. Both are essentially described in patents, from which straighforward data concerning the sttucture of the products and the outcome of the reactions are difficult to extract. For silicone glycosides, some descriptions can be found, only in patents, for example in US 5,428,142 [2]. They are usually prepared by a Fischer... 

Graft copolymers have been found to show higher acid resistance in comparison to natural polysaccharides. This increase in acid resistance is due to the incorporation of poly(vinyl) chains onto vulnerable sites like -OH and CHjOH groups [60, 78, 79] (Figure 2.9). 

Incorporation of hydrophobic poly(vinyl) moieties through graft copolymerization onto natural polysaccharides results in the decrease of base sensitivity... 

Furthermore, the more there is of the branched base of the polysaccharide, the greater the opportunity the grafted (onto polysaccharide backbone) poly-acrylamide/cationic moiety chain will have to form an aggregate of the contaminants. Thus, if the grafted moiety is loaded onto the most hyperbranched polysaccharides, it will have easier accessibility to form aggregates of the contaminants, providing the best flocculation characteristics. 

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