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Poly drug release from hydrogels

When the fractional drug release from an initially dehydrated hydrogel sheet is plotted as a function of square root of time as shown in Figure 1 for thiamine HC1 release from a poly(2-hydroxyethyl methacrylate) sheet, linearity in the plot is observed only at large times. This illustrates the non-Fickian and time-dependent nature... [Pg.72]

Coughlan, D. C., Quilty, F. R, Corrigan, O. I. (2004). Effect of drug physicochemical properties on swelling/deswelling kinetics and pulsatile drug release from thermorespon-sive poly(lV-isopropylacrylamide) hydrogels. Journal of Controlled Release, 98,97-114. [Pg.33]

Okuyama, Y, Yoshida, R., Sakai, K., Okano, T, Sakurai, Y. SweUing controlled zero-order and sigmoidal drug release from thermoresponsive poly(N-isopropylacrylamide-co-butyl methacrylate) hydrogel. J. Biomater. Sci. Polym. 4, 545-556 (1993)... [Pg.364]

Hydrogels were synthesized by cross-linking HA with DVS and poly (ethylene glycol)-functionalized divinyl sulfone (VS-PEG-VS). These gels were loaded with vitamin E succinate (VES) and bovine serum albumin (BSA), as models of antiinflammatory proteins and drugs, and their release kinetics were measured in vitro. The rate of release from HA-VS-PEG-VS-HA hydrogels was faster than that from HA-DVS-HA hydrogels, presumably because of the lower cross-linked density in the former (75). [Pg.340]

See other pages where Poly drug release from hydrogels is mentioned: [Pg.350]    [Pg.208]    [Pg.27]    [Pg.19]    [Pg.380]    [Pg.2033]    [Pg.158]    [Pg.307]    [Pg.605]    [Pg.286]    [Pg.230]    [Pg.146]    [Pg.273]    [Pg.236]    [Pg.29]    [Pg.36]    [Pg.270]    [Pg.773]    [Pg.792]    [Pg.1737]    [Pg.287]    [Pg.162]    [Pg.278]    [Pg.149]    [Pg.137]    [Pg.69]    [Pg.79]    [Pg.158]    [Pg.87]    [Pg.429]    [Pg.1221]    [Pg.2033]    [Pg.1744]    [Pg.146]    [Pg.1374]    [Pg.551]    [Pg.197]    [Pg.207]    [Pg.433]    [Pg.103]    [Pg.287]    [Pg.327]    [Pg.142]    [Pg.25]    [Pg.1472]   
See also in sourсe #XX -- [ Pg.202 ]



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Poly hydrogels

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