Poly -based glycopolyme

Scheme 16.17 (A) Asymmetrical, bifunctional dendrimer 69 containing 16 mannose units and two coumarin chromopbores and (B) poly(methacrylate)-based glycopolymer 70 prepared by CuAAC and used for lectin binding studies with concanavalin A...

Some reviews have been published on the synthetic carbohydrate-based polymers and glycopolymers [11-15]. However, they refer mainly to poly(vinylsaccharide)s and other conventional functionalized polymers having sugars as groups pendant from the main chain of the polymer. In this chapter we shall describe those sugar-based monomers which lead to polymers having the sugar units incorporated into... 

Figure 7.11 ROMP-derived monolith based on tris(methyl carboxylate)ethane (a) containing PONBE and PNBE, and (b) containing PONBE and poly(cyclooctene) (PCC ). (c) Neo-glycopolymer synthesized via tandem ROMP-hydrogenation.

Their hydrophilicity arises from the presence of water-solubilizing groups such as —OH, —COOH, —CONH2, —CONH—, —SO3H, and so on. Alternately, the main chain of the polymer may be water soluble, such as poly(ethylene oxide) derivatives (122), or based on acrylic, acrylamide, A-vinyl-2-pyrrolidinone, poly (vinyl alcohol), ionomers or glycopolymers (123). The insolubility arises from the presence of a three-dimensional network. The cross-links may be covalent, electrostatic, hydrophobic, or dipole-dipole in character. The extent of hydration may exceed a factor of 100, based on dry gel weight. 

Phosphorus-Based Polymers From Synthesis to Applications 12 Poly(lactic acid) Science and Technology Processing, Properties, Additives and Applications 13 Cationic Polymers in Regenerative Medicine 14 Electrospinning Principles, Practice and Possibilities 15 Glycopolymer Code Synthesis of Glycopolymers and their Applications... 

Zhu JM, Gosen C, Marchant RE (2006) Synthesis and characterization of poly(vinyl amine)-based amphiphilic comb-like dextran glycopolymers by a two-step method. J Polym Sci A Polym Chem 44(1) 192-199... 

Figure 4.2 Glycopolymer-based gene delivery vectors a) Linear polymer b) Hyperbranched polymer c) NP d) CNT and e) Nanogels. EDC l-ethyl-3-(3-dimethylaminopropyl) carbodiimide NHS N-hydroxysuccinimide P(APMA- -LAEMA) poly(3-aminopropyl methacrylamide-block-2-lactobionamidoethyl methacrylamide) and SWCNT single-walled carbon nanotube(s).

---