Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Pneumocandins

Echinocandins B-D -lipopeptide antibiotics and other peptides including aculeacin A, mulundocandin, and pneumocandins... [Pg.54]

Denning DW. (1997) Echinocandins and pneumocandins — a new antifungal class with a novel mode of action. J Antimicrob Chemother 40 611-614. [Pg.138]

Cyclic hexapeptides can be considered as the classical and the most prominent representatives among cyclic peptides. Natural products are numerous and widespread (see Scheme 11), e.g. segetalin A,[278] bouvardin/279280 RA-IIlJ281-283 or pneumocandin B0,[284 286] and this type of ring structure has frequently been used to stabilize conformational preferences of bioactive portions of larger peptides or even proteins. [Pg.479]

Scheme 11 Structures of the Naturally Occurring Cyclic Hexapeptides Segetalin A, 2781 Bouvardin, 279-2801 Pneumocandin b, 284-2861 and of a Synthetic Cyclic Somatostatin Analogue 2871... Scheme 11 Structures of the Naturally Occurring Cyclic Hexapeptides Segetalin A, 2781 Bouvardin, 279-2801 Pneumocandin b, 284-2861 and of a Synthetic Cyclic Somatostatin Analogue 2871...
DM Schmatz, G Abruzzo, MA Powles, DC McFadden, JM Balkovec, RM Black, K Nollstadt, K Bartizal. Pneumocandins from Zalerion arboricola. IV. Biological evaluation of natural and semi-synthetic pneumocandins for activity against Pneumocystis carinii and Candida species. J Antibiot 45 1886-1891, 1992. [Pg.243]

Improved In Vivo Efficacy with Stepwise Amino Modifications of Pneumocandin Bga b... [Pg.440]

Compound name pneumocandin Bq modification TOKAc EDqq 9 Activity (mg/kg) Aspergilla ed50 PCP ED90... [Pg.440]

Fig. 3. Morphological effects of pneumocandin treatment on Aspergillus and Candida. Panel 1 Light micrographs of drug-induced morphologic changes in A. fumigatus showing (A) control fungus and (B) effect of treatment of 2 pg/ml of L-733,560 (reproduced with permission from Kurtz et al, 1994). Fig. 3. Morphological effects of pneumocandin treatment on Aspergillus and Candida. Panel 1 Light micrographs of drug-induced morphologic changes in A. fumigatus showing (A) control fungus and (B) effect of treatment of 2 pg/ml of L-733,560 (reproduced with permission from Kurtz et al, 1994).
See other pages where Pneumocandins is mentioned: [Pg.26]    [Pg.217]    [Pg.323]    [Pg.227]    [Pg.229]    [Pg.423]    [Pg.431]    [Pg.431]    [Pg.432]    [Pg.432]    [Pg.437]    [Pg.437]    [Pg.437]    [Pg.438]    [Pg.439]    [Pg.440]    [Pg.441]    [Pg.441]    [Pg.442]    [Pg.442]    [Pg.444]    [Pg.445]    [Pg.448]    [Pg.450]    [Pg.452]    [Pg.453]    [Pg.455]    [Pg.19]    [Pg.29]    [Pg.216]    [Pg.414]    [Pg.414]    [Pg.414]    [Pg.415]    [Pg.255]   
See also in sourсe #XX -- [ Pg.3 , Pg.9 ]

See also in sourсe #XX -- [ Pg.22 , Pg.23 , Pg.69 , Pg.343 ]

See also in sourсe #XX -- [ Pg.69 ]

See also in sourсe #XX -- [ Pg.76 , Pg.137 , Pg.139 ]

See also in sourсe #XX -- [ Pg.343 ]



SEARCH



Pneumocandin

Pneumocandin

The Pneumocandins Mycology and Parasitology Collide

© 2024 chempedia.info