Platinum complexes amides

The generalized application of the aminolysis of halophosphanes has been the method of choice for the preparation of a wide variety of chiral phosphinous amides by starting from enantioenriched primary amines [36]. The aminolysis reaction occurs efficiently even when the halophosphane is placed in the coordination sphere of a metal, as in the palladium and platinum complexes of the type ds-M(Ph2PCl2)2Cl (M=Pd, Pt) [37,38]. 

Pinacolone, o-(diphenylphosphino)benzoyl-coordination chemistry, 401 Piperidine, IV-hydroxy-metal complexes, 797 pA a values azole ligands, 77 Plant roots amino acids, 962 carboxylic acids, 962 Plastocyanin copper binding site, 557 copper(II) complexes, 772 copper(II) site in, 770 Platinum, dichlorobis(benzonitrile)-IR spectrum, 264 Platinum, cis-dichlorodianunine-antitumor activity, 34, 979 Platinum, ethylenebis(triphenylphosphine)-reactions with 5,6-dimethyl-2,l,3-benzothiadiazole, 194 Platinum blue formation, 265 Platinum complexes acetylacetone reactions, 380 amides, 491 amidines... 

Deammoniation of this product at 130°C. gives platinum (II) amide. Similar reactions have been carried out with the ethylenediamine complex of platinum(II), and both the singly deprotonated product, [Pt(en)(en-H)]I, and the doubly deprotonated product, [Pt(en-H)2], were isolated as solid products and characterized (60). Later work showed that under proper conditions a white solid could be obtained which behaved as K[Pt(en-H)(en-2H)] (57). Each of these deprotonated species behaves as a strong base in aqueous solution, and the original material, [Pt(en)2] ", is regenerated. 

PC8HM, Phosphine, dimethylphenyl-, 22 133 iridium complex, 21 97 PC 2H27, Phosphine, tributyl-, chromium complexes, 23 38 PC18H1S, Phosphine, triphenyl-, 21 78 23 38 cobalt complexes, 23 24-25 cobalt, iridium, and rhodium complexes, 22 171, 173, 174 iridium complex, 21 104 palladium complex, 22 169 palladium and platinum complexes, 21 10 ruthenium complex, 21 29 PNOC 2Hl2, Phosphinic amide, diphenyl-, lanthanoid complexes, 23 180 PNAH.2, Propionitrilc, 3,3, 3 -phosphinidy-netri-,... 

The doubly bridged cobalt and, in one case, platinum complexes contain an 0 and an amide or hydroxo bridge.The superoxo... 

Several ruthenium and platinum complexes catalyse the reductive N-heterocyclisation of N-(2-nitrobenzoyl)amides (51) under carbon monoxide pressure to afford the corresponding 4(3H)-quinazolinone derivatives (52) in good yields (eq. 26, Tables 16 and 17) [90] ... 

Recently, some other boron carriers were used to deliver polyhedral boranes into tumor cells. One of the most interesting and new direction is developments in the BNCT driven by nanotechnology [142-147]. This subject will not be discussed here since a special chapter is planned in this book. Carboranylquinazolines [148], carboranyl aminoalcohols [149], carboranyl-a-acyloxy-amides [150], carboranyl glycophosphonates [151], conjugates of icosahedral dicarboranes with cobalt bis(dicarbollide) [152], and platinum complexes containing carborane [153] have been obtained as potential candidates for BNCT. 

Some Pt complexes bearing electron-donating phosphines can also catalyze the hydration of the C=C double bond of acrylonitrile or crotonitrile and yielded P-hy-droxypropionitrile or P-hydroxybutyronitrile respectively besides the corresponding amide (Eq. 6.38) [22, 75], Among the platinum phosphine complexes examined, [Pt(PEt3)3] (26a), carrying less bulky ligands, was the most effective for the hydration of the olefmic bond. The present catalyst system was ineffective for hydration of other olefins, however. 

In a study of the hydrolysis of platinum(II)-nitrile complexes to afford the corresponding amides, the first well-characterized examples of platinum(II) complexes that dimerize spontaneously to form weakly bonded Pt-Pt dimers with an unsupported intermetallic bond have been described.166 For example, treatment of cw-[PtCl2(NCBut)2] with excess KOH affords the amide species cw-[PtCl2 HN=C(OH)But 2], which exists as a dimer (49) both in solution and in the solid state, with a Pt-Pt bond length of 3.165(1) A, as determined by X-ray crystallography. Four... 

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