Plasmalogens antioxidant

Plasmalogen (antioxidant), acylcamitine (transport), CL (respiration), PS (cofactors, substrate of PE synthesis), etc. 

Fig. 9.4 Chemical structures of cellular lipids that act as endogenous antioxidants. Choline plasmalogens (a) ethanolamine plasmalogens (b) ganglioside (c) and vitamin E (a-tocopherol) (d)...

Engelmann B. (2004). Plasmalogens targets for oxidants and major lipophilic antioxidants. Biochem. Soc. Trans. 32 147-150. 

Zoeller R. A., Lake A. C., Nagan N., Gaposchkin D. R, Legner M. A., and Lieberthal W. (1999). Plasmalogens as endogenous antioxidants somatic cell mutants reveal the importance of the vinyl ether. Biochem. J. 338 769-776. 

Murphy, RC (2001) Free-radical-induced oxidation of arachidonoyl plasmalogen phospholipids Antioxidant mechanism and precursor pathway for bioactive eicosanoids. Chem Res Toxicol, 14,463-472. 

Plasmalogen species play many roles in cellular functions in addition to serving as a biomembrane component. Previous studies demonstrated that membranes comprised of plasmalogen species possess a compact membrane conformation and unique membrane dynamics in comparison to membranes comprised of its diacyl counterpart [75-78]. A central role of plasmalogen PE in facilitating membrane fusion and cell-cell communication [79, 80] was demonstrated and the propensity for membrane fusion is directly linked with the quantity of the double bonds present in the GPL acyl chains of the membrane [81]. The role of plasmalogen as an antioxidant... 

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