Piper guineense, alkaloids

Several new alkaloids have been isolated from pepper species. Tricholeine, for example, occurring in the stems of Piper trichostachyon, is the pyrrolidine amide (2) of fra s-9-(3,4-methylenedioxyphenyl)-A8-nonenoic acid, the structure being established by spectroscopic and degradative studies.4 Piper guineense seeds contain okolasine (6-methoxytrichostachine) (3),5 which is probably identical to the earlier known wisanidine. 4,5-Dihydro-wisanidine (4) is also found in the same... 

Sharma s group has also synthesized guineensine, which is the alkaloid produced by both Piper guineense and P. officinarum.14 The isolation of trans- and cis-(—)-clovamides and their deoxy-analogues from the bark of Dalbergia... 

Piper guineense Schumach et Thonn West African black pepper, Ashanti pepper Piperaceae Neuromuscular activity, contraceptive, antiparasitic, aphrodisiac Abdominal disorders, chest complaints, used as an enema. Bronchitis, Headache, An1helmintic,Caries, diarrhea, hemorrhoids, antibiotic. Alkaloidal amide, 12, 16, 17... 

Several representatives of the genus Piper (Piperaceae) are of economic importance. Some of these plants [e.g.. Piper nigrum (black pepper)] include alkaloids that are partially responsible for the desirable pungent and preservative properties of the plant. Other species are P. hetle (widely used as a masticatory), P. methysticum (widely used in the South Pacific as a soporific drug), and P. guineense (ashanti pepper). Most of these plants contain compounds that combine phenylpropanoid compounds see Chapter 8) and pyr-... 

---