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Pinacolyl methylphosphonofluoridate

Drug solutions and implantation of osmotic mini-pumps Physostigmine hemisulphate and procyclidine hydrochlorid were obtained from Sigma (St.Louis, U.S.A.), scopolamine hydrobromid from Merck (Darmstadt, Germany), atropine sulphate was obtained from ACF (Amsterdam, The Netherlands), and diazepam from Roche (The Netherlands). HI-6 was made available by the Defence Research Establishment, Suffield, Canada. Soman (O-pinacolyl methylphosphonofluoridate) was synthesised at TNO. Alzet Osmotic Mini-pumps with a constant delivery rate of 0.55 pl/hr (Model 2002, Alza Corp., Palo Alto, USA) were used to deliver PYR, PHY and SCO. The vehicle consisted of 20% propylene glycol, 10% ethanol and 70% water. The pumps were implanted subcutaneously under isoflurane/02 inhalation anesthesia. [Pg.115]

Soman (pinacolyl methylphosphonofluoridate), called GD in the United States, is a moderately volatile substance that can be taken by inhalation or skin contact. [Pg.275]

Fleisher, J.H., Harris, L.W. 1965. Dealkylation as a mechanism for aging of cholinesterase after poisoning with pinacolyl methylphosphonofluoridate. Blochem. Pharmacol. 14 641-650. [Pg.317]

Soman, TrUon, Pinacolyl methylphosphonofluoridate, Methylphosphonofluoridic acid,... [Pg.24]

Sarin, TrUon 46, Isopropylmethylphosphonofluoridate, Isopropylmethylphosphoryl fluoride Sarin-ethyl, Sarin-II, Isopropylethylphosphonofluoridate, Isopropylethylphosphoryl fluoride Sarin-ethyl, Sarin-11, Isopropylethylphosphonofluoridate, Isopropylethylphosphoryl fluoride Sarin-isopropyl, Sarin-111, Isopropyl-2-propylphosphonofluoridate, Isopropoxy-2-propylphosphoryl fluoride Sarin-isopropyl, Sarin-111, Isopropyl-2-propylphosphonofluoridate, Isopropoxy-2-propylphosphoryl fluoride Soman, TrUon, Pinacolyl methylphosphonofluoridate, Methylphosphonofluoridic acid,... [Pg.51]

GBE, 12, 40, 66, 92, 114, 118, 167. See also Sarin-ethyl, sarin-II, isopropylethylphosphonofluoridate, isopropylethylphosphoryl fluoride GBI, 12, 40, 66, 93, 114, 118, 168. See also Sarin-isopropyl, sarin-III, isopropoxy-2-propylphosphonofluoridate, isoproxy-2-propylphosphoryl fluoride GD, 13, 40, 66, 93, 115, 117-119, 166-167, 179, 182, 186. See also Soman, trilon, pinacolyl methylphosphonofluoridate, methylphosphonofluoridate, methylphosphonofluoridic acid, 1,2,2-tri-methylpropyl ester... [Pg.281]

Pinacolyl methylphosphonofluoridate Methylphosphonofluoridic acid 1,2,2-tri-methylpropyl ester Tabun-II... [Pg.356]

Soman. It is Methylpinacolyloxyfluoro-phosphine Oxide, Monopinacolicester of methylfluorophosphoric Acid or Pinacolyl-methylphosphonofluoridate,... [Pg.203]

Patocka, J. (1989). Effect of pyridostigmine and syntostigmine pretreatment on the inhibition of acetylcholinesterase by o-pinacolyl-methylphosphonofluoridate. In vitro experiments with rat tissues. Biomed. Biochim. Acta 48 715-20. [Pg.983]

Other names for this agent include (1) O-pinacolyl methylphosphonofluoridate, (2) pinacolyl methylphosphonofluoridate, (3) EA1210, (4) methyl pinacolyl phosphonofluoridate, (5) methyl pinacolyloxy phosphoryl fluoride, (6) T-300, and (7) PMFP. It carries CAS 96-64-0. Thickened soman (TGD) (aka VR-55) is created by adding thickener to GD. [Pg.39]

Harris LW, Braswell LM, Fleisher JP, Chff WJ. Metabohtes of pinacolyl methylphosphonofluoridate (Soman)... [Pg.543]

Hambrook JL, Howells DJ and Utley D (1971). Degradation of phosphonates. Breakdown of soman (O-pinacolyl-methylphosphonofluoridate) in wheat plants. Pest Sci, 2, 172-175. [Pg.122]

Harris, L.W., Braswell, L.M., Fleisher, J.H., and Cliff, W.J., Metabolites of pinacolyl methylphosphonofluoridate (soman) after enzymatic hydrolysis in vitro, Biochem. Pharmacol., 13, 1129, 1964. [Pg.91]

Vojvodic, V. and Milosevic, M., Some pharmacological actions of oximes and atropine on the cadiovascular effects produced by pinacolyl methylphosphonofluoridate (soman) in rats, lugosl. Physiol. Pharmacol. Acta, 7, 439, 1971. [Pg.94]

See other pages where Pinacolyl methylphosphonofluoridate is mentioned: [Pg.764]    [Pg.915]    [Pg.122]    [Pg.689]    [Pg.437]    [Pg.444]    [Pg.710]    [Pg.128]    [Pg.285]    [Pg.356]    [Pg.168]    [Pg.196]    [Pg.23]    [Pg.211]    [Pg.211]    [Pg.337]    [Pg.92]    [Pg.183]    [Pg.102]    [Pg.110]    [Pg.193]    [Pg.194]    [Pg.410]    [Pg.684]    [Pg.210]   
See also in sourсe #XX -- [ Pg.94 ]

See also in sourсe #XX -- [ Pg.94 ]

See also in sourсe #XX -- [ Pg.94 ]

See also in sourсe #XX -- [ Pg.496 ]



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