Picornavirus RNA Contain a Second Termination Site

Does Picornavirus RNA Contain a Second Termination Site  

Secondary processing products of pi10 (coat protein) and p90 are not shown. 

Are the Three Primary Products PI, S and P2 Located in One Translational Cistron or Two  

Assuming for the mRlTA of rhinovirus 1A a mass of 2.6 million daltons this leaves some 25-30 kD, of the theoretical 270 kD protein-coding capacity, -unaccounted for. With one significant 

On the other hand the existence of non-coding regions involved, for example, in replicase recognition at either end of the RNA molecule would not be surprising. In addition it is not yet possible to exclude the possibility of still undetected protein especially if it were the product of a cistron which is translated at a lower frequency than the major one. This returns us to an important omission in our picornaviral map, the position of the viral capping protein which is covalently bound to the of the picornaviral 

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