Phytophthora capsid

Miyakado, M., Kato, T., Ohno, N. and Koshimuzi, K. 1975. Alkaloids of Urginea altissima and their antimicrobial activity against Phytophthora capsid. Phytochemistry, 14 2717. 

Clairjeau, M., and Beyries, A. 1977. Etude compar e de l action preventive et du pouvoir systAmique de quelques fongicides nouveaux (phosphites-prothiocarb-pyroxychlore) sur poivron vis-A-vis de Phytophthora capsid (Lion). Phytlatr. Phytopharm. 26, 73-83. 

Moreau RA, Young DH, Danis PO, Powell MJ, Quinn CJ, Be-shah K, Slawecki RA, Dilliplane RL. Identification of ceramide-phosphorylethanolamine in oomycete plant pathogens pythium ul-timum, ph)4ophthora infestans, and phytophthora capsid. Lipids 1998 33 307-317. 

The covalent binding property of benzamides has been exploited in the development of cell-based competitive binding assays that measure the ability of other antitubulin agents to inhibit binding of radiolabeled benzamides to j -tubulin in whole cells. The tritiated S-enantiomer of zoxamide has been used to study the zoxamide binding site in the Oomycete Phytophthora capsid [7]. Tritiated analogs 2 and 3 (RH-4032 and RH-5854, Fig. 16.1.2) have been used in similar assays in plant [4] and mammalian cells [6], respectively. 

The experimental benzamide fungicide zarilamide (4, Fig. 16.1.3 below) was discovered by ICI in the 1980s [8] and was found to act on microtubules [9]. Zarilamide was later shown to inhibit H-(S)-zoxamide binding to j -tubulin in Phytophthora capsid in a competitive manner [7], indicating a common binding site with zoxamide. 

Bower, L. A., Coffey, M. D. Development of laboratory tolerance to phosphorous acid, fosetyl-Al, and metalaxyl in Phytophthora capsid. Can. J. Plant Pathol. (1985) 7, 1-6. 

Kim BS, Lee JY, Hwang BK. In vivo control and in vitro antifungal activity of rhamnolipid B, a glycohpid antibiotic, against Phytophthora capsid and Colletotrichum orhiculare. Pest Manag Sci 2000 56 1029-35. 

Xu, J. G., Zhao, X. M. Han, X. W. (2007).Antifungal activity of oligochitosan against Phytophthora capsid and other plant pathogenic fungi in vitro. Pesti Biochem Physiol., 87, 220-228. 

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