Physical chemistry of biological

KJ Stine. In A Baskin, W Norde, eds. Physical Chemistry of Biological Interfaces. New York Marcel Dekker, 1999, pp 749-768. 

Kleijn, J. M. and van Leeuwen, H. P. (2000). Electrostatic and electrodynamic properties of biological interphases. In Physical Chemistry of Biological Interfaces. eds. Baszkin, A. and Norde, W., Marcel Dekker, New York, pp. 49-63. 

One of the points made in Schwenz and Moore was that the physical chemistry laboratory should better reflect the range of activities found in current physical chemistry research. This is reflected in part by the inclusion of modem instrumentation and computational methods, as noted extensively above, but also by the choice of topics. A number of experiments developed since Schwenz and Moore reflect these current topics. Some are devoted to modem materials, an extremely active research area, that I have broadly construed to include semiconductors, nanoparticles, self-assembled monolayers and other supramolecular systems, liquid crystals, and polymers. Others are devoted to physical chemistry of biological systems. I should point out here, that with rare exceptions, I have not included experiments for the biophysical chemistry laboratory in this latter category, primarily because the topics of many of these experiments fall out of the range of a typical physical chemistry laboratory or lecture syllabus. Systems of environmental interest were well represented as well. 

Current Topics Physical Chemistry of Biological Systems... 

In the development of modem experiments, there were a large number of experiments developed using lasers and the NMR. More development would be welcome in experiments using MS, AFM, and STM. In addition, more experiments devoted to characteristics of modem materials, to environmental chemistry, and especially to the physical chemistry of biological and biologically relevant systems are needed. 

Peacocke, A. R. (1983). An Introduction to the Physical Chemistry of Biological Organization . Clarendon Press, Oxford. 

Baszkin, A. and Norde, W. 2000. Physical Chemistry of Biological Interfaces. Marcel Dekker, New York. 

This book is about the physical chemistry of biological macromolecules and how we can study it. The approach here is unashamedly experimental this is the way science actually works, and in any case we do not yet have the rigorous theoretical understanding perhaps found in more mature areas of chemistry. This is what makes it a fun topic, and why it poses fascinating challenges for both theoretical and experimental scientists. 

Urry DW. Physical chemistry of biological free energy transduction as demonstrated by elastic protein-based polymers. J Phys Chem B 1997 101 11007-11028. 

D.W. Urry, Physical Chemistry of Biological Free Energy Transduction as Demonstrated by Elastic Protein-based Polymers, invited Feature Article, J. Phys. Chem. B, 101, 11007-11028, 1997. 

D.W. Urry, Physical Chemistry of Biological Free Energy Transduction as Demonstrated by... 

There is much hope that fundamental research into stem cell biology can eventually be translated into cell-based therapies to treat human disease. Stem cells possess the ability of selfreplication and can be expanded in culture. Stem cells can also be genetically modified and differentiated into aU of the cells comprising tissues that may 1 day be replaced or repaired via tissue-engineering applications. Rapid advances in materials chemistry, photolithography, microfabrication, and microfluidics have provided important new analytic approaches and have led to new insights into the physical chemistry of biological behavior at the subcellular and molecular levels [1]. 

Lyklema, J. Interfacial thermodynamics with special reference to biological systems, in Physical Chemistry of Biological Interfaces, A. Baszkin and W. Norde (eds.). Marcel Dekker, New York, Chapter 1, 2000. 

The hydrogen gas produced in this manner can be used as a fuel in a variety of other devices. The preceding is an example of how a careful study of the physical chemistry of biological systems can yield not only surprising insights but also new technologies. 

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