Photosensitization photosensitizers

Antibiotics Cephalosporins Chloramphenicol Neomycin Sulfathiazole Spiramycin Quinolones Tetracyclines Hypersensitivity Anaphylaxis, urticaria, rash, granulocytopenia Rash, dermatitis, urticaria Dermal exposure-rash, dermatitis Rash, dermatitis, urticaria Rash, dermatitis, urticaria Photosensitivity Photosensitivity, anaphylaxis, asthma, dermatitis... 

Photosensitivity Photosensitization (photoallergy or phototoxicity) may occur therefore, caution patients to take protective measures (ie, sunscreens, protective clothing) against exposure to sunlight or ultraviolet light (eg, tanning beds) until tolerance is determined. 

Diabetes me///fws Triamterene may raise blood glucose levels for adult-onset diabetes dosage adjustments of hypoglycemic agents may be necessary. Concurrent use with chlorpropamide may increase the risk of severe hyponatremia. Photosensitivity Photosensitization is likely to occur avoid prolonged exposure to sunlight. 

Photosensitivity Photosensitization may occur. Caution patients to take protective measures against exposure to sunlight or ultraviolet light until tolerance is determined. 

Photosensitivity Photosensitivity manifested by an exaggerated sunburn reaction has been observed in some individuals taking tetracyclines. Advise patients who are apt to be exposed to direct sunlight or ultraviolet light that this reaction can occur with tetracycline drugs, and discontinue treatment at the first evidence of skin erythema. 

Porphyria In patients with porphyria, these drugs have precipitated an acute attack. Photosensitivity Photosensitization (photoallergy or phototoxicity) may occur. Renal/Hepatic function impairment Jse with caution. The frequency of renal complications is considerably lower in patients receiving the more soluble sulfonamides (sulfisoxazole and sulfamethizole). 

Byrd DR+, Mayo Clin Proc 72, 930 (photosensitive) Photosensitivity (I -10%)... 

On the other hand, inhibiting effect of nitroxylic radical at irradiation is not observed owing to its strong action as photosensitizer. Photosensitization is absent after irradiation in dark reaction and nitroxylic radical displays its inhibiting action. That is why oxidation after irradiation (post-effect) is not observed (Figure 2.7, curve 2). 

J. Moan, K. Berg, E. Kvam, A. Western, Z. Malik, A. Ruck, H. Schneckenburger (1989). Intracellular localization of Photosensitizers. Photosensitizing Compounds their Chemistry, Biology and Clinical Use (Ciba Foundation Symposium 146, pp. 95-111). Wiley, Chichester. 

Photosensitizer Photosensitizer Dose (mg/kg) Interval (hours) Energy Dose J/cm (l) or J/cm (2) Wavelength (nm) Indications... 

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