Photomicrographs showing visual

The importance of a visual technique, such as HSM, lies in its ability to provide information for the confirmation of transitions that are observed using other techniques. As stated earlier, the characterization of the physical properties of many materials, including pharmaceuticals, requires a multidisciplinary approach in which a number of techniques are utilized to confirm suspect transitions. To illustrate the need for this characterization philosophy, several examples, along with numerous photomicrographs showing the benefit that a visual technique such as HSM can provide, are presented. 

Figure 1. Photomicrographs showing the visual cue of the 91/9 wt/wt D,L-PLA/PCL-PDO blend burr hole cover plate after (right) heating above the melting transition of the PCL-PDO copolymer and after the plate has cooled to body temperature and been implanted in a rabbit cranium (left)...

Photo Ic is a photomicrograph of IPS that contained no light stabilizers which was exposed outdoors in Florida for six months. Note the total loss of surface integrity including deep surface crazes. This photo also shows the mildew that was visually present along with their typical hyphal structures. 

Fig. 3. Glomeruli. Photomicrographs of the main olfactory bulb showing the glomeruli that are especially well visualized by A. immunohistochemical staining with an antibody to olfactory marker protein (OMP) or B. histochemistry using cytochrome oxidase.

X-ray diffraction analysis and photomicrographs obtained by transmission electron microscopy (TEM) indicated that the clay was intercalated by the polymer and almost completely exfoliated. Photomicrographs obtained by TEM shows the morphology of some nanocomposites (Fig. 8). It is obviously possible to visualize... 

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