Phosphorochloridates phosphoryl chlorides

PHOSPHORYLATION 2-Chloromethyl-4-nitrophenyl phosphorochloridate. o-Phenyl-ene phosphorochloridate. Phosphoryl chloride. Phosphoryl chloride-Trimethyl phosphate. 

Phosphorylation O-Benzyl phosphorus 0,0-diphenylphosphoric anhydride. 2-Cyanomethyl phosphate. Dibromomalonamide. Di-p-nilrobenzylphosphoryl chloridate. Dioxane diphosphate. Diphenylphosphorochloridate. Ethoxyacetylene. Metaphosphoric acid. o-Phenyl-ene phosphorochloridate. Phosphoric acid, anhydrous. Phosphorodimorpholidic chloride. Phosphorus pentoxide-Phosphoric acid. Phosphoryl chloride. Polyphosphoric acid. Pyro-phosphoryl tetrachloride. Silver dibenzyl phosphate. Silver diphenyl phosphate. Tetra-p-nitrophenyl pyrophosphate. 

Polyfluoroalkyl phosphorodichloridates and bis(poly-fluoroalkyl) phosphorochloridates have been prepared from the corresponding alcohols. The reactions between polychloro-1-nitrosoethanes and phosphorus(III) chlorides have provided the phosphoryl chlorides (3) and (4) whilst the same procedure... 

Synonyms Diphenyl phosphorochloridate Diphenyl phosphoryl chloride DPCP Phosphorochlorendic acid diphenyl ester... 

Diphenyl phosphonate. See Diphenyl phosphite Diphenyl phosphorochloridate Diphenyl phosphoryl chloride. See Diphenyl chlorophosphate Diphenyl phthalate... 

Although the phosphorochloridic acids are, in principle, related as in (5.263), they are more difficult to isolate than their fluoro analogues. Phosphorodichloridic acid can be prepared by the hydrolysis of pyrophosphoryl chloride at -60°C (5.279) or from phosphoryl chloride and water (5.280). It is a clear liquid, stable in the absence of air and has a melting point of -18°C. 

Mixed alkyl aryl esters may be obtained by reacting phosphorochloridates with sodium derivatives of phenols or alcohols (5.297, 5.298). Octyl diphenyl phosphate is obtained commercially by reaction (5.298), the starting material having been obtained from octyl alcohol and phosphoryl chloride by a reaction of type (5.295). 

Phosphorins, tetrahydro-17, 798 Phosphorochloridates (s. a. Bis-(l-imidazolid-2-onyl)-phosphoryl chlorides, Phosporodichloridates, Pyrocatechyl phosphoro-trichloridate)... 

D-Fructose i-phosphate was first prepared by phosphatase action on fructose i,6-diphosphate °. It is formed enzymically by condensation of dihydroxyacetonephosphate and D-glyceraldehyde and from fructose and ATP " . Synthesis has been carried out by treating 2,3,4,5-diiso-propylidene-D-fructopyranose with phosphoryl chloride , or PjOj , or diphenyl phosphorochloridate . 

Chloride [6087-94-1]. Bis(2-chloroethyI) phosphorochloridate. Bis 2-chloroethyl) phosphoryl chloride... 

Used for gravimetic detn. of Fe(//7) and for extraction of rare earth elements. Needles or plates. Mp 133-135°. Chloride [15074-53-0]. Bis 4-chlorophenyl) phosphorochloridate. Bis 4-chlorophenyl) phosphoryl chloride. Bis(4-chlorophenyI) chlorophosphate C,2H8Cl303P M 337.525... 

A synthetic approach to /3-sultams containing a direct bond between a tri- or tetracoordinated phosphorus atom and the nitrogen atom of the 1,2-thiazetidine 1,1-dioxide ring has been realized by direct phosphitylation or phosphorylation at nitrogen. Unfortunately, attempts to synthesize N-phosphorylated /3-sultams by reaction with diethyl phosphorochloridate and diethyl phosphorobromidate, generated in situ from diethyl phosphate and carbon tetrachloride or carbon tetrabromide, failed. However, when the /3-sultam is treated with freshly distilled diethyl phosphorochloridite or tetramethylphosphorodiamidous chloride in the presence of triethylamine, the expected AHliethy I phosphite and iV-phosphorodiamidous /3-sultams 150 are obtained (Equation 10). /3-Sultams unsubstituted... 

Diphenyl phosphorochloridate is one of the most widely employed phosphorylating reagents for the preparation of phosphomonoesters (Scheme 3.17a).94 The chloride acts as a leaving group that can be displaced by hydroxyls. The phenyl groups act as protecting groups that... 

Some 1- and 2-hydroxyalkanephosphonates have been successfully resolved by a CALB (Candida antarctica lipase B)-catalysed acylation process to give both (R)- and (S)-isomers with high enantiomeric excess (in most cases with 95% ee). (S)-Naproxen and (S)-Ibuprofen chloride are convenient chemical derivatizing agents for the determination of the enantiomeric excess of hydroxy and aminophosphonates by PMR. . New phosphorylating agents, 3-phosphoro-2(-N-cyanoimino)-thiazolidine derivatives (3-phosphoro-NCTS) (316), can be used as a stable alternative to phosphorochloridates. Phosphoryla... 

According to the original process of Addor (1962), phospholan is prepared by the reaction of ethylene-1,2-dithiol with cyanogen chloride, followed by the reaction of 2-imino-l,3-dithiolane (103) with diethyl phosphorochloridate. According to his later process (1970), N-(0,0-diethylphosphoryl) dithiocarbamate (104), obtained by the addition reaction of diethyl phosphoryl isothiocyanate and potassium hydrosulilde, is cyclised with ethylene bromide. 

As described above, the l-(or 3-) hydroxyl group of myo-inositol has higher reactivity over other equatorial hydroxyls. This tendency was observed in the following examples. Phosphorylation of 155 with diphenyl phosphorochloridate produced the 1,3-diphosphate 156 predominantly in moderate yield together with 1,5-diphosphate 157 (Scheme 3-24).15,55 Benzylation of the triol 155 under PTC conditions led to the 1-benzyl ether 158 in 71% yield (overall yield from the orthoester 95 in three steps). The resultant tetrabenzyl ether 158 was again regioselectively acylated at C-3 with camphanic acid chloride for resolution (Scheme 3-24).42... 

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