Phosphoglyceric acid mutase

Rodwell, V. W., Towne, J. C. and Grisolia, S. (1956) Crystalline phosphoglyceric acid mutase. Biochim. Biophys. Acta, 20, 394. 

Imidazole (histidine) Phosphoglycerate mutase, succinyl-CoA synthetase, nucleoside diphosphokinase, histone phosphokinase, acid phosphokinase Phosphorylenzyme... 

Pemtothenic Acid, 230 Papain, 429 Pectins, 63 Peptidases, 428 Peptides, 148 Phosphatidyl choline, 82 Phosphatidyl ethanolamine, 83 Phosphatidyl glycerol, 84 Phosphofructokinase Regulation, 281 Phosphoglycerate Kinase, 286 Phosphoglycerate Mutase, 286 Phosphoproteins, 151 Photorespiration, 484 Photosynthesis, 471 Pih, 10 Plant CeU, 16... 

Fig. 1 Three-dimensional representation of phosphoglycerate mutase left) [47] and rat prostatic acid phosphatase (right). Based on Schneider et al. [1]...

His —f= Acid phosphokinase, histone phosphokinase, nucleoside diphosphokinase, phosphoglycerate mutase, succinyl- phosphorylenzyme... 

The Citric Acid Cycle (or the Tricarboxylic Acid [TCA] Cycle or the Krebsi Cycle). It will be recalled (Schemes 11.24-11.26) that the enzyme phosphoglycerate mutase (EC 5.4.2.1) acts on PGA (obtained from, e.g., fructose-1,6-bisphosphate) to produce the isomeric, 2-phosphoglycerate and that phosphopyruvate hydratase (EC 4.2.1.11) then converts the 2-phosphoglycerate to phosphoenolpyruvate. 

The carbon flow from 3-phosphoglycerate, phosphoenolpyruvate, pyruvate and acetyl-CoA. Even if the synthesis of aromatic amino acids by shikimate pathway /28,29,30,31/ and also prenyl-PP synthesis via mevalonate /32,33,34/ has been established in chloroplasts by identification of respective plastidic enzymes, it is still a matter of discussion from where PEP origins to supply DAHP synthesis of the shikimate pathway and from where pyruvate is delivered to supply the plastidic pyruvate dehydrogenase complex (for isolation see Treede and Heise, this Conference). Because phosphoglycerate mutase (PGM) to form 2-PGA from 3-PGA could not be detected in chloroplasts /35/ and acetyl-CoA is preferably synthesized from added acetate by the actetyl-CoA synthetase /36/, particularly in spinach chloroplasts, it was argued that chloroplasts are dependent on import of these substrates from the external site. Evidence for PEP formation from 3-PGA within the chloroplast could be obtained by three different approaches (D. Schulze-Siebert, A. Heintze and G. Schultz, in preparation D. Schulze-Siebert and G. Schultz, in preparation, for plastidic isoenzyme of PGM in Ricinus see /37/ and in Brassica /38/). 

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