Phloretic acid

Tyrosine was now regarded as ethylamidopara-oxybenzoic acid on reduction, therefore, it should yield ethylamine, but instead of this Hufner, in 1868, obtained ammonia, and he supposed tyrosine to be amidophloretic acid. This view was strengthened when Barth in the following year obtained p-oxybenzoic acid from phloretic acid and also from Schmidt and Nasse s base. This here garded as... 

Until igoo phloretic acid had the constitution OH. C,H4. CH. COOH, but in that... 

The phenolics ( + )catechin and (— )epicatechin are common flavanols in several fruits (128). Apples and pears contain other phenolic compounds such as quinic, shikimic, chlorogenic, and caffeic acids (39). Durkee and Poapst (162) reported that the two major phenolic constituents of core tissues and seeds of McIntosh apples were chlorogenic acid and phloridzin. After hydrolysis of extracts from core tissues, the identified phenolics were phloretin, caffeic acid, p-coumaric acid, phloretic acid, and trace amounts of ferulic acid. Studies have shown that apple leucoanthocyanins yield catechin, epicatechin, cyanidin, and pelargonidin after hydrolysis (163, 164). Van Buren et al. (164) also reported that a purified leucoanthocyanin from apples was either a dimer or oligomer containing ( —) epicatechin, and 5,7,3, 4 -flavin-3,4-diol. 

Bromination of a simple tyrosine analog, phloretic acid (p-hydroxy-phenylpropionic acid) (CIV), tvith two equivalents of reagent in aqueous... 

Phloretic acid Reductase Lact. plantamm Lact. fermentum Lact. reuteri... 

The syntheses of telechelic, star-shaped or hyperbranched oligo- and polyesters reported in this work are based on two "a-b monomers" 3-hydroxy-benzoic acid (3-Hybe) and 3-(4 -hydroxyphenyl)propionic acid (phloretic acid, Phla). These monomers were selected for the following reasons. Polyesters of 3-Hybe melt below 200°C, and they are soluble in various organic solvents (10). Polycondensations of 2-Hydroxybenzoic acid derivatives show a high tendency to yield cyclic oligomers and substituted and imsub-... 

Materials 3-Hydroxy-, 3,5-dihydroxy, 3-amino- and 3,5-diaminobenzoic acid were gifts of BAYER AG (Leverkusen, FRG) and used without further purification. Bisphenol-P and bisaniline-P were purchased from Kennedy and Klim (Little Silver, N.J., USA). Piperazine, l,l,l-tris(4 -hydroxy-phenyl)ethane, phloretic acid tetrahydroxy spirobisindane were purchased from Aldrich Co. (Milwaukee, Wise., USA). All hydroxy acids and phenols were acetylated with an excess of acetic acid and a catalytic amount of pyridine in refluxing toluene. All silylations were conducted with chloro-trimethylsilane and triethylamine in refluxing toluene or dioxane. 

---