Phillips, David

Patrick T. Naughtin Mickey G. Huson Brett O. Bateup Francis W. Jones John R. Christoe Les N. Jones Allan G. De Boos Keith R. Millington Ron J. Denning David G. Phillips David J. Evans TonyJ. Pierlot G. Bruce Guise John A. Rippon Barry V. Harrowfield Rob A. Rottenbury Bill Humphries Ian M. Russell CSIRO... 

Zhao, C., Wang, D., Phillips David, L. Theoretical study of samarium (II) carbenoid (ISmCH2l) promoted cyclopropanation reactions with ethylene and the effect of THF solvent on the reaction pathways. J. Am. Chem. Soc. 2003, 125, 15200-15209. 

Phillips, David (1979). William Lawrence Bragg. Biographical Memoirs of Fellows of the Royal Society of London 22 381-413. 

Phillips, David, and Thomas, John Meurig, eds. (1990). Selections and Reflections The Legacy of Sir Lawrence Bragg. Northwood, U.K. Science Reviews. 

Phillips David The Royal Institution 21 Albemarle Street London WIX 4BS U.K. 

William Serson, Maythem AL-Amery, Shreya Patel, Tim Phillips, David F. Hildebrand... 

Figure 2.10 Examples of schematic diagrams of the type pioneered by Jane Richardson. Diagram (a) illustrates the structure of myoglobin in the same orientation as the computer-drawn diagrams of Figures 2.9b-d. Diagram (b), which is adapted from J. Richardson, illustrates the structure of the enzyme triosephosphate isomerase, determined to 2.5 A resolution in the laboratory of David Phillips, Oxford University. Such diagrams can easily be obtained from databases of protein structures, such as PDB, SCOP or CATH, available on the World Wide Web.

Hen egg-white lysozyme catalyzes the hydrolysis of various oligosaccharides, especially those of bacterial cell walls. The elucidation of the X-ray structure of this enzyme by David Phillips and co-workers (Ref. 1) provided the first glimpse of the structure of an enzyme-active site. The determination of the structure of this enzyme with trisaccharide competitive inhibitors and biochemical studies led to a detailed model for lysozyme and its hexa N-acetyl glucoseamine (hexa-NAG) substrate (Fig. 6.1). These studies identified the C-O bond between the D and E residues of the substrate as the bond which is being specifically cleaved by the enzyme and located the residues Glu 37 and Asp 52 as the major catalytic residues. The initial structural studies led to various proposals of how catalysis might take place. Here we consider these proposals and show how to examine their validity by computer modeling approaches. 

Walter of Odington. David Ragor s transcription of Walter of Odington s "Icocedron." By Phillip Drennon Thomas. Some notes on research in Austrian archives, by Martin A. Reif. Wichita Wichita State Univ, 1968. 32p. 

David P. Phillips, Gwendolyn E. C. Barker, and Megan M. Eguchi, A Steep Increase in Domestic Fatal Medication Errors with Use of Alcohol and/or Street Drugs, Archives of Internal Medicine 168, no. 14, July 28, 2008, pp. 1,561-1,566. Also available online. URL http //archinte.ama-assn.org/cgi/ content/short/168/14/1561. Downloaded April 17, 2009. 

Lysozyme is a natural antibacterial agent found in tears and egg whites. The hen egg white lysozyme (Mr 14,296) is a monomer with 129 amino acid residues. This was the first enzyme to have its three-dimensional structure determined, by David Phillips and colleagues in 1965. The structure revealed four stabilizing disulfide bonds and a cleft containing the active site (Fig. 6-24a see also Fig. 4-18). More than five decades of lysozyme investigations have provided a detailed picture of the structure and activity of the enzyme, and an interesting story of how biochemical science progresses. 

I also wish to express my appreciation to David Strasfeld, Gil Nathanson, John Harriman, and (particularly) Bob Bird, who suggested helpful improvements to an early draft to Mark Wendt, who prepared the rendered graphics for the cover and Figure 11.1 and to John Herbert, Phillip Thomas, and David Strasfeld (all former teaching assistants in Chem 561), who assembled problems and exercises to accompany the book. 

Department of Chemistry, The University of Texas, Austin, Texas DAVID PHILLIPS... 

The elucidation of the structure of ribonuclcasc follows that of lycozyme by a group at London s Royal Institute headed by Dr. David C. Phillips, and that of the other protein, myoglobin, for which Dr. Max F. Perutz and Dr. John C. Kendrew of Cambridge University received the Nobel Prize in chemistry in 1962. 

In 1963, the first volume of Advances in Photochemistry appeared. It was founded by W. Albert Noyes, Jr., along with George Hairanond and James N. Pitts, Jr. Therefore, it is fitting that we dedicate the rebirth of this series, which was discontinued temporarily after Volume 12 appeared in 1980, to his memory. Many of the review articles that have appeared in earlier issues of Advances in Photochemistry were written by his former graduate students and postdoctoral fellows. These include R. Srinivasan, Derrick Hoare, Hideo Okabe, Jacques LeMaire, Israel Unger, Julian Heicklen, David Phillips, and Gerald Porter. 

Saper, Robert B., David M. Eisenberg, and Russell S. Phillips. "Common Dietary Supplements for Weight Loss." American Family Physician 70 no. 9 (November 1, 2004) 1731. Available online. URL www.aafp.org/afp/20041101/1731.html. Accessed November 13, 2007. 

David A. Pethick, Pres., Energy Environment Frank C. Gross, Pres., Industrial Process Greg P. Therrien, Pres., Infrastructure Chris L. Phillips, COO/Pres., Rust Constructors, Inc. 

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