Phenyl methanol

Pyrolysis of bis(trimethylsilyl)phenyl methanol 1668 at 500 °C leads, via elimination of trimethylsilanol 4, to the carbene intermediate 1669, which rearranges, via the carbene intermediate 1670, to give l,2-dimethyl-2,3-benzo-l-silacyclopent-2-ene 1671, in 25% yield, or rearranges via olefin 1672 and adds 4 to give the siloxane 1673 in 29% yield and smaller amounts of benzyltrimethylsilane 83 and styrene [43, 44]. Pyrolysis of l,l-bis(trimethylsilyl) cyclohexylalcohol 1674 furnishes, via the carbene intermediate 1675, 90% of olefin 1676 [43, 44] (Scheme 10.20). 

Lewis, T. W. Curtin, D. Y. Paul, I. C. Thermal, photochemical and photonucleated thermal dehydration of /j-hydroxytriary I methanols in the solid state. (3,5-Dimethyl-4-hydroxyphenyl)diphenyl methanol and (3,5-dibromo-4-hyrdoxyphenyl)di phenyl methanol X-ray crystallography of (4-hydroxyphenyl)diphenyl methanol and its 3,5-dimethyl derivative. J. Am. Chem. Soc. 1979, 101, 5717-5725. 

Synonyms AI3-01680 Benzal alcohol Benzene carbinol Benzene methanol Benzoyl alcohol Benzylicum BRN 0878307 Caswell No. 081F CCRIS 2081 EINECS 202-859-9 EPA pesticide chemical code 009502 Elydroxymethylbenzene a-Elydroxytoluene NC1-C06111 NSC 8044 Phenol carbinol Phenyl carbinol Phenyl methanol Phenyl methyl alcohol a-Toluenol UN 2810. 

Phenyl hydrate, see Phenol Phenyl hydride, see Benzene Phenyl hydroxide, see Phenol Phenylic acid, see Phenol Phenylic alcohol, see Phenol Phenylmethane, see Toluene Phenyl methanol, see Benzyl alcohol Phenyl methyl alcohol, see Benzyl alcohol iV-Phenylmethylamine, see Methylaniline... 

The reaction is a Michael type of addition to a base-induced dehydration product of the (4-hydroxy phenyl) methanol. 

The reaction of 2-aminobenzyl alcohol 376 with 2-chloro-4,5-dihydroimidazole afforded [2-(4,5-dihydro-177-imidazol-2-ylideneamino)phenyl]methanol hydrochloride 377, which upon treatment with carbon disulfide gave l-(477-3,l-benzoxazin-2-yl)imidazolidine-2-thione 378 (Scheme 71). The assumed reaction mechanism involved the initial formation of the dithiocarbamate 379, which underwent intramolecular nucleophilic addition to furnish the unstable thiazetidine 380. By nucleophilic attack of the hydroxy group on the carbon atom of the thiazetidine ring, thiocarbamate derivative 381 was formed, which gave the final 3,1-benzoxazine 378 by an intramolecular cyclocondensation with the evolution of H2S <2006H(68)687>. 

The initially patented synthesis of cetirizine (4) by UBC S. A. in Belgium was an extension of the hydroxyzine (41) synthesis.Gngnard addition to p-chlorobenzaldehyde gave (4-chloro-phenyl)-phenyl-methanol, which was easily brominated using PBrs in benzene to give 4-chlorodiphenylmethyl bromide (42). Sn2... 

Propanol, 2-methyl-l-propa-nol, cyclohexanol, phenyl-methanol AI2 O3 130—240 117... 

The phenylmethoxycarbonyl (benzyloxycarbonyl) group can be introduced by way of the corresponding acyl chloride, which is prepared from phenyl-methanol (benzyl alcohol) and carbonyl dichloride ... 

Arylmethyl chlorides or bromides are quite reactive compounds that are readily available or easily prepared, and as a result they are useful intermediates for the synthesis of other side-chain derivatives. Thus phenylmethyl chloride can be hydrolyzed to phenyl methanol, converted to phenylethanenitrile with alkali-metal cyanides, and oxidized to benzenecarbaldehyde (benzaldehyde) ... 

A palladium-catalyzed intramolecular 1,4-dialkoxylation of (2-(cyclohexa-l,5-dienyl)phenyl)methanol provides a stereocontrolled route to isochromans 542 (Equation 224) <1998TL1223>. A tandem nucleophilic allylation-alkoxyal-lylation reaction of an ortio-alkynylbenzaldchydc 543, allyl chloride and allyltributylstannane in the presence of allylpalladium chloride furnishes the isochroman 544 via a (i-mdo-diycycl ization process (Equation 225) <2002TL7631 >. 

A theoretical study of the chiral recognition of the bis(amino(phenyl)methanol) chromium(O) complexes and chiral discrimination of the dimers of amino(phenyl) methanol linked by HB has been carried out by means of a DFT method, the B3LYP/6-31+G. The results (Fig. 3.24) show that in the chromium complexes, the homochiral one is preferred over the heterochiral one, while the opposite... 

K. Zborowski et al., A theoretical study of chiral recognition in bis[amino (phenyl) methanol] chromium(O) complexes. Pol. J. Chem. 81, 621-629 (2007)... 

Gas-phase pyrolysis of 3-(177-pyrrol-2-yl)prop-2-en-l-ol 25 (R= H) (650°C, lO -lO Torr) and [2-(l//-pyrrol-2-yl)phenyl]methanol 27 (700 °C, 10 Torr) causes loss of water and cyclization to give 3//-pyrrolizines 26 (Equation 2) and 28 (Scheme 9) in 66-95% yield <1999J(P1)2049>. At 650 °C, a number of unidentified by-products were present in the pyrolysate from the tertiary alcohol 25 (R = Me), but 3,3-dimethyl-3//-pyrrolizine 26 was obtained in satisfactory yield and purity (64% after distillation) when pyrolysis was carried out at 550 °C. 

TCPMe, and 4,4, 4"-TCPM for tris(4-chlorophenyl)methane. In this chapter the abbreviations TCPM and TCPMe will be used. TCPM and TCPMe (Fig. 1) are structurally related to DDT and dicofol (l,l,l-trichloro-2,2-bis(4-chloro-phenyl)methanol) (Fig. 2). 

Benzenemethanol a-hydroxytoluene phenylcarbinol phenyl-methanol a-toluenol. 

Synonyms Benzene carbinol Benzene methanol Benzoyl alcohol Phenyl carbinol Phenyl methanol Hydroxymethyl benzene Hydroxy toluene... 

A number of substituted cyelopropanes have been prepared by reductive lithiation of various l,l-bis(phenylsulfanyl)cyclopropanes followed by reactions of the resulting a-phenylsulfanyl-cyclopropyl anions with selected electrophiles. Metalation can be carried out by several methods, cf 1, ° but reduction with two equivalents of lithium naphthalenide in tetrahyd-rofuran at — 70°C is the most efficient. The product yields are generally satisfactory with carbon dioxide and benzaldehyde as trapping agents. Thus, when 2-methyl-1,1-bis(phenylsul-fanyl)cyclopropane was used as starting material, 2-methyl-l -(phenylsulfanyl)cyclopropanecar-boxylic acid (2 b) and (2-methyl-l-phenylsulfanylcyclopropyl)(phenyl)methanol (3 c) were obtained in 86 and 76% yield, respectively. ... 

Chlor-benzophenonkannmitZinkinNatronlauge(l,5Stdn. 110°, 5 Stdn. 120-125°) unter Erhalt der Cl-Aryl-Bindung in 94%iger Ausbeute bei 96°/0iger Reinheit zu Phenyl-(4-chlor-phenyl) -methanol reduziert werden1. 

Benzyl Alcohol Benzenecarbinol Alpha- Hydroxytoluene Phenylcarbinol Phenyl- Methanol Phenylmethyl Alcohol... 

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