Phencyclidine analogs

Shannon, H.E. Evaluation of phencyclidine analogs on the basis of their discriminative stimul us proper ti es in the rat. J. 

Vaupel, D.B. McCoun D. and Cone, E.J. Phencyclidine analogs and precursors Rotarod and lethal dose studies in the mouse. J... 

Itzhak, Y., and Simon, E.J. A novel phencyclidine analog interacts selectively with mu opioid receptors. J. Pharmacol Exp Ther... 

Alexander Sasha" Shulgin (1925- ) Meperidine Analogs Phencyclidine Analogs GHB and Rohypnol Guesses and Risks... 

Ketamine is a cyclohexane human and veterinary injectable anesthetic that is also known by the slang names K, special K, vitamin K, and cat Valium (Bobo and Miller 2002). It is produced in a liquid form or as a white powder and is usually ingested orally or intranasally but is occasionally administered intramuscularly. Ketamine is a phencyclidine (PCP) analog that was first developed in 1962. 

Quirion, R. Rice, K.C. Skolnick P. Paul, S. and Pert, C.B. Stereospecific displacement of 3H phencyclidine (PCP) receptor binding by an enantiomeric pair of analogs. Eur J. 

Albuquerque, E.X. Warnick, J.E. Aguayo, L.G. Ickowicz, R.K. Blaustein, M.P. Maayani, S. and Weinstein, H. Phencyclidine Differentiation of behaviorally active from inactive analogs based on interactions with channels of electrically excitable membranes and of cholinersic receptors. In Kamenka, J.M. Domino, E.F. and Geneste P., eds. Phencvclidine and Related Arvl hexvl ami nes Present and Future Appl i cat ions. Ann Arbor ... 

Altura, B.T. Quirion, R. Pert, C.B. and Altura, B.M. Phencyclidine (angel dust) analogs and "sigma" opiate benzomorphans cause cerebral arterial spasm. Proc Natl Acad Sci II.SA 80 865-869, 1983. 

J.E. and Albuquerque, E. X. Descriminant effects of behavioral -ly active and inactive analogs of phencyclidine on membrane electrical excitability. J. Pharmacol Exp Ther 228 80-87, 1984. Albuquerque, E.X. Tsai, M.C. Aronstam, R.S Witkop, B. ... 

Solomon, R.E. Herling, S. Domino, E.F. and Woods, J.H. Discriminative stimulus effects of N-substituted analogs of phencyclidine in rhesus monkeys. Neuropharmacoloav 21 1329-1336, 1982. 

E. J. Cone, Separation and identification of phencyclidine precursors, metabolites and analogs by gas and thin-layer chromatography and chemical ionization mass spectrometry, J. Chromatogr., 777 149(1979). 

Aromatic and f-basic features are also linked to a quaternary center in phencyclidine (18, PCP), a well-known drug of abuse.(24) In the MHP test, PCP was not active up to 9 mg/kg sc (higher doses caused ataxia) but its analog 20 proved about twice as effective as morphine.(25) The activity of 20 fell 10-fold after esterification with propionic acid so the compound appears... 

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