Pharmacokinetics hallucinogens

An important consideration in this context is that the extent of retention may vary with the urine pH, if the drug molecule is a weak acid or base. An example of applied pharmacokinetics from the underground is LSD (lysergic acid diethylamide Figure 2.21). While a powerful hallucinogen, it is allegedly quite unpredictable whether the hallucinations will actually turn out pleasant or more along the lines of Count Dracula. In the latter case, it has been recommended to follow up the LSD with lots of vitamin C (ascorbic acid). 

Summary. In spite of the sketchy records, BZ appears to be an anticholinergic hallucinogen quite comparable with JB-329 (Dltran) or others of Che JB series or with scopolamine. The onset of effects Is usually rapid, regardless of the route of administration, and the duration Is often a function of the dose. Although pharmacokinetic data on these compounds In man are unavailable, there is some evidence of a dose-response relationship. Without treatment to counter Che effects of these strong central... 

Mechanisms of Action of LSD-Like Drugs Pharmacokinetics of LSD-Like Drugs Psychotherapeutic Uses Effects of Serotonergic Hallucinogens Adverse Effects of Serotonergic Hallucinogens... 

Drug metabolism, 259 Gastrointestinal agents, 56 Hallucinogens, 13 Hypnotics, 28 Muscle relaxants, 28 Neurotransmitters, 270 Parameters, physicochemical, 314 Pharmaceutics, 302 Pharmacokinetics, 302 Physicochemical parameters, 314 Pulmonary drugs, 67 Reactions in Medicinal Chemi stry, 291 Reproduction, 189 Sedatives, 28 Steroid hormones, 199 Steroids, 281 Stimulants, 13 Vasoconstrictors, 77 Vasodilators, 77... 

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