Pharmacokinetics clinical applications

Subclass Mechanism of Action Pharmacokinetics Clinical Applications Toxicities, Interactions... 

Yamamura S (2003) Clinical application of artificial neural network (ANN) modeling to predict pharmacokinetic parameters of severely ill patients. Adv Drug Deliv Rev 5 1233-1251. 

I.6.I. Radioactive Isotopes. The administration of isotopically labeled drugs is now commonplace in the experimental pharmacology of every new therapeutic agent (K18, M4) but has little or no clinical application. It often provides much of the initial information about the pharmacokinetics upon which subsequent clinical practice depends, but... 

Theophylline is one of the mainstays of therapy for acute and chronic obstructive airways disease. Until recently little was known about its pharmacokinetics and their clinical application, but there is now good evidence (J4) that both the therapeutic response and toxic side effects are related to the concentration of theophylline in plasma, rather than to its dosage. 

Parveen S, Sahoo SK. Nanomedicine clinical applications of polyethylene glycol conjugated proteins and drugs. Clin Pharmacokinet 2006 45 966-88. 

Ritschel WA, Kearns GL. Handbook of basic pharmacokinetics. .. including clinical applications. 6th ed. Washington (DC) American Pharmaceutical Association 2004. 

Holford NGH, Sheiner EB. Elnderstanding the dose-effect relationship clinical application of pharmacokinetic-pharmacodynamic models. Clin Pharmacokinet 1981 6 429-53. 

PHARMACOKINETIC CHARACTERISTICS INFLUENCING THE CLINICAL APPLICATION OF INTRAVENOUS AND INHALATIONAL ANESTHETICS ... 

The increasing use of stimulants in the United States to treat attention deficit hyperactivity disorder (ADHD) has aroused parental concern and compelled both medical professionals and the media to question the safety and efficacy of this type of treatment. Because ADHD is among the most common reasons for seeking mental health services for children, these questions are more pertinent than ever. This chapter will examine the history of stimulant use, the mechanism of action, pharmacokinetics, side effects, and issues related to their clinical use in children and adolescents. More detailed information on clinical applications is provided in Section III. 

Clinical Application of Pharmacokinetic Principles Single-Dose Predi,ctip,n,Te ... 

Subclass Mechanism of Action Effects Clinical Applications Pharmacokinetics, Toxicities... 

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