Pharmacogenomics definitions

There is widespread indiscriminate use of, and thus confusion about the terms pharmacogenetics and pharmacogenomics . While no universally accepted definition exists, there is emerging consensus on the differential connotation of the two terms (see Tab. 6.1). 

There is a diversity of opinion regarding definitions and benefits of pharmacogenetics and pharmacogenomics.1 3 For example, pharmacogenetics is often considered to be the study of inter-individual variations in DNA sequence related to drug absorption and disposition (pharmacokinetics, PK) or drug action (pharmacodynamics, PD). Polymorphic variation in the genes that encode the functions of transporters,... 

Genomics and pharmacogenomics is not the only omics of importance. Some we quoted without much explanation above. You will definitely never be fully able to bluff your way through modem healthcare cocktail parties if you do not know the latest precise definitions of the omics and other terms that have come up in the news over the past five years or so. We have already discussed the established ones. At the time of writing, recent offerings and some new spins on the old, are as follows ... 

Pharmacogenomics in a paediatric setting -some history and definitions... 

E12 clinical evaluation by therapeutic category E14 chnical evaluation E15 definitions in pharmacogenetics/ pharmacogenomics E16 qualification of genomic biomarkers... 

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