Peptides fibrillization

Preparation of mixed peptide fibrils was similar for both of these labelled peptides 1% (by weight) was incubated at 37 °C with the other, unlabelled peptide in 10% CH3CN/H20atpH2.ForTTRio i9with l%dansyl-TTRio5 n5, a blue shift and dansyl anisotropy increase were observed, indicating the inclusion of dansyl-TTRios-i 15 into fibrils. CD spectroscopy proved that the stmcture was primarily p-sheet. 

Meegan JE, Aggeli A, Boden N et al (2004) Designed self-assembled beta-sheet peptide fibrils as templates for silica nanotubes. Adv Fund Mater 14 31-37... 

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Fu X, Wang Y, Huang L, Sha Y, Gui L, Lai L, Tang Y. Assemblies of metal nanoparticles and self-assembled peptide fibrils—formation of double helical and single-chain arrays of metal nanoparticles. Adv Mater 2003 15 902-906. 

Mesquida P, Ammann DL, MacPhee CE, McKendry RA. Microarrays of peptide fibrils created by electrostatically controlled deposition. Adv Mater 2005 17 893-897. 

Meegan, J.E., Aggeli, A., Boden, N., Brydson, R., Brown, A.P., Carrick, L., Brough, A.R., Hussain, A., and Ansell, R.J. "Designed self-assembled beta-sheet peptide fibrils as templates for silica nanotubes". Adv. Fund. Mater. 14(1), 31-37 (2004). 

Sunde M, et al. Common core structure of amyloid fibrils by synchrotron X-ray diffraction. J. Molec. Biol. 1997 273 729. Tjemberg LO, et al. A molecular model of Alzheimer amyloid beta -peptide fibril formation. J. Biol. Chem. 1999 274 12619-12625. Benzinger TLS, et al. Two-dimensional structure of beta-Amyloid (10-35) fibrils. Biochem. 2000 39 3491-3499. 

Massi, F. Straub, J.E. Energy landscape theory for Alzheimer s amyloid p-peptide fibril elongation. Proteins Struct. Funct. Genet. 2001, 42, 217-229. 

De Eerrari, G. V., Canales, M. A., Shin, 1., Weiner, L. M., Silman, 1., Inestrosa, N. C. A structural motif of acetylcholinesterase that promotes amyloid beta-peptide fibril formation. Biochemistry, 2001, 40, 10447-10457. 

Formation of Large-Scale Metal-Peptide Fibrils and Spheres... 

Amyloid Peptide Fibrils. Solid state NMR measurements have been reported... 

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