Pentyl nitrite

Methylpyridazine can be oxidized with selenium dioxide to give 3-formylpyridazine, and methyl groups attached to any position in pyridazine N-oxides are transformed with pentyl nitrite in the presence of sodium amide in liquid ammonia into the corresponding... 

Both 2- and 3-methyl groups in pyrido[2,3-Z ]pyrazines are acylated by ethyl oxalate (71TH21500). They give (preferentially 3-) styryl derivatives with aromatic aldehydes and oximes with pentyl nitrite. 

Methyl isothiazole-4-acetate is nitrosated by pentyl nitrite, and the oximino ester formed can be hydrolyzed to the a-keto ester (78GEP2745246). Secondary alcohols (94) can be oxidized to the ketones (72GEP2223648). 

Pentyl amine, see n-Amylamine Iso-Pentyl nitrite, see Amyl nitrite Peracetic acid (40% acetic acid solution)... 

Cyclization of 3-hydrazinotriazines 712 with cyanogen bromide afforded [76JCS(P1)1492] the hydrobromide of a weakly basic amine 721 via intermediate 720. Deamination of 721 with pentyl nitrite gave triazolo [4,3-6][l,2,4]triazine 722. Similarly, 7-oxo analogues were obtained (81JHC1353). 

The sum of all results is consistent with the formation of both the aryl cation and the aryl radical in the aqueous acid system without copper, and with the dominance of the aryl radical in the presence of copper. The product ratios are also qualitatively consistent with the hypothesis that the reactivity of aryl cations with nucleophiles is close to that of a diffusion-controlled process (see Sec. 8.3), and that aryl radicals have arylation rate constants that are about two orders of magnitude smaller than that for diffusion control (0.4-1.7 X 107 m-1s-1 Kryger et al., 1977 Scaiano and Stewart, 1983). Due to the relatively low yields of these dediazoniations in the pentyl nitrite/benzene systems, no conclusions should be drawn from the results. 

N-Methylmorphollne 1-Nitropef>tane Pentyl nitrite tsopentyl nitrite Pentyl nitrate... 

Pentanone, see Methyl n-propyl ketone 3- Pentanone, see Diethyl ketone Pentene, see Amylene n-Pentyl acetate, see n-Amyl acetate sec-Pentyl acetate, see sec-Amyl acetate Pentyl alcohol, see n-Amyl alcohol Pentyl amine, see n-Amylamine iso-Pentyl nitrite, see Amyl nitrite Peracetic acid (40% acetic acid 1.23 41... 

See Other CATALYTIC IMPURITY INCIDENTS, A-OXIDES 11998. Pentyl nitrite... 

Several approaches to the 1,2,3-triazole core have been published in 2000. Iodobenzene diacetate-mediated oxidation of hydrazones 152 led to fused 1,2,3-triazoloheterocycles 153 <00SC417>. Treatment of oxazolone 154 with iso-pentyl nitrite in the presence of acetic acid gave 1,2,3-triazole 155, a precursor to 3-(W-l,2,3-triazolyl)-substituted a,P-unsaturated a amino acid derivatives <00SC2863>. Aroyl-substituted ketene aminals 156 reacted with aryl azides to provide polysubstituted 1,23-triazoles 157 <00HC387>. 2-Aryl-2T/,4/f-imidazo[43-d][l,2,3]triazoles 159 were prepared from the reaction of triethyl AM-ethyl-2-methyl-4-nitro-l//-imidazol-5-yl phosphoramidate (158) with aryl isocyanates <00TL9889>. 

One of the two enthalpies of formation for the tertiary alkyl nitrites is most probably incorrect. As seen in Table 1, not only is the slope for the liquid-phase data less negative than that for the gas-phase data, but it is much less steep than all other liquid-phase data of which we know. Part of the discrepancy is due to the inverted order of the archival enthalpies of vaporization t-butyl nitrite = 34.4 kJmol-1 and t-pentyl nitrite = 33.5 kJ mol 1. 

The diazotization of heteroaromatic amines is basically analogous to that of aromatic amines. Among the hve-membered systems the amino-azoles (pyrroles, diazoles, triazoles, tetrazoles, oxazoles, isooxazoles, thia-, selena- and dithiazoles) have all been diazotized. In general, diazotization in dilute mineral acid is possible, but diazotization in concentrated sulfuric acid (nitrosylsulfuric acid, see below) or in organic solvents using an ester of nitrous acid (ethyl or 2-pentyl nitrite) is often preferable. Amino derivatives of aromatic heterocycles without ring nitrogen (furan and thiophene) can also be diazotized. 

Decyl nitrite, 3364 f Ethyl nitrite, 0867 f Isopentyl nitrite, 1996 f Isopropyl nitrite, 1262 f Methyl nitrite, 0455 f Pentyl nitrite, 1998 f Propyl nitrite, 1265... 

Typical nitrosating agents are sodium nitrite with mineral acids or pentyl nitrite with mineral acids. A relatively new reagent, nitrosylsulfuric acid, has been used to nitrosate primary aromatic amines. 

Tertiary aromatic amines have also been nitrosated with pentyl nitrite in hydrochloric acid [21a],... 

The reaction may be carried out either by the addition of nitrosyl chloride or by the generation of this reagent in situ from pentyl nitrite and hydrochloric acid. 

Acetoxylation of fS,y-unsaturated esters.3 / ,y-Unsaturated esters are oxidized by PdCI2-CuCl-02 to y-keto esters in 20 40% yield. Reaction of these esters with PdCl2 and KOAc and pentyl nitrite (oxidizes Pd(0)] under oxygen leads to y-aceloxy-a,/ -unsaturated esters (45- 55% yield). The double bond has the (reconfiguration (equation I). 

---