PENTANOIC ACID, 4-METHYL-3-OXO

Ethyl 2-butyrylacetate Pentanoic acid, 4-methyl-3-oxo-, ethyl ester (9) (7152-15-0)... 

ZK 216348 another nonsteroidal structure (Figure 9.4) has been made and characterized by scientists from Bayer Schering Pharma AG [71]. The compound is a pentanoic acid 4-methyl-l-oxo-lH-2,3-benzoxazinamide bearing a trifluoromethyl-and a hydroxyl group at the a-carbon and an additional methyl and phenyl group at the (D-end resulting in a compound with two quaternary carbons. 

Difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-s-indacene-3-pentanoic acid 4,ll-bis[(2-Aminoethyl)amino]anthra[2,3-b]furan-5,10-diones 4(l-Anilino-podophyllotoxin derivatives 5-Aza-2 -deoxycytidine 5-Bromotetrandrine 5-Cyclohexylindolyl-2 -deoxyribose (non-natural nucleoside) 5 -Fluorosulfonylbenzoyl 5 -adenosine 5-Fluorouracil 5,5-Diphenylbarbituric acid 6-[(2S,4R,6E)-4-Methyl-2-(methylamino)-3-oxo-6-octenoic acid] cyclosporine D (PSC833) 6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid 6-Mercaptopurine 6-Prenylchrysin 6-Thioguanine 6,7-Dimethoxy-... 

Diastereoselective alkylation of (R)-(-F)-camphor-based glycylimine (19) with 3-bromo-2-fluoropropene gave (R)-(-F)-2-amino-4-fluoropent-4-enoic acid with 38% overall yield and 90% ee after hydrolytic deprotection, or in the case of the alanylimine, (R)-(-F)-2-amino-4-fluoro-2-methyl-pent-4-enoic acid (19% overall yield, 59% ee) [49]. Deprotection under drastic conditions was accompanied by hydrolysis of the fluorovinyl moiety to give (R)-(-)-2-amino-4-oxo-pentanoic acid hydrochloride with 28% overall yield and >95% ee (Scheme 4). 

Urea, (2,5-dioxo-4-imidazolydinyl)-, compd. with N-(3-hydroxymethyl-3-methyl-2-hydroxybutanoyl)-3-aminopropanoic. See Allantoin calcium pantothenate Urea, (2,5-dioxo-4-imidazolydinyl)-, compd. with olean-12-en-29-oic acid, 3p-hydroxy-11-oxo-. See Allantoin glycyrrhetinic acid Urea, (2,5-dioxo-4-imidazolydinyl)-, compd. with 2H-thieno [3,4- d] imidazole-4-pentanoic acid, hexahydro-2-oxo-, [3as-(3aa,4b,6aa)]. See Allantoin biotin... 

The priority order enables us to decide that molecule (a) is an acid, in fact a pentanoic acid. But what prefix do we use for the carbonyl group The prefix oxo-is used to indicate either an aldehyde or a ketone as a substituent. We name the molecule 3-methyl-4-oxopentanoic acid. 

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