2 ,3 ,4 ,5,7-Pentahydroxyflavone

UV-Vis linear dichroism and (mid-)IR ATR IR analysis have been used to explain the possible association between DNA and the flavonols quercetin, rutin (quercetin-3-rutino-side), and morin (3,5,7,2, 4 -pentahydroxyflavone) in solution.These nucleophilic flavonoids were shown to bind DNA by intercalation with an interaction having similar nature and geometry however, under comparable conditions, quercetin exhibited a greater number... 

Hydroxychalcone (chalcone) 4 -Hydroxvchalcone (chalcone) Morin ( = 3,5,7,2, 4 -Pentahydroxyflavone) (flavonol)... 

Technical morin (3,5,7,2, 4 -pentahydroxyflavone) is supplied by Eastman, Baker, and Matheson, Coleman and Bell. A solution of 300 n of morin in 500 ml. of methanol is added with stirring to a slurry of 500 g. of alumina in 500 ml. of methanol. When the supernatant liquor is decolorized, the alumina is collected and dried at 150° for 2 hrs., when the citron-yellow preparation has grade II activity." A column of this adsorbent fluoresces in ultraviolet light (ca. 360 m/r), and colorless substances that absorb in the near ultraviolet show up on the column as dark bands on a luminous background. It proved useful for separation of naturally occurring polyunsaturated diols."... 

Several other color reactions may be used for the identification of titanium dioxide, after solubilization of the material. Pyrocatechol yields a yellowish-red color with weakly acidified solutions of titanium salts [12]. When chromotropic acid is reacted with solubilized titanium between pH 2.5 and 5.0, a wine red colored solution is obtained [13]. An intense brown color is given by the addition of acidic solutions of 3,5,7,2 ,4 -pentahydroxyflavone (morin) to titanium salts, although the composition of the product is unknown [14]. 

Morin reagent is also used for the detection of peptides. The developed plates are dried and sprayed with 0.05% morin (3,5,7,2, 4 -pentahydroxyflavone) solution in methanol and activated for 2 min at 100°C. In this case, the peptides produce yellowish-green fluorescent spots on a green fluorescent background or dark absorption spots under UV hght. The detection limit is just about 2 p,g/spot. Detection of P-labelled opioid peptides is done by autoradiography. 

Five oiganotin compounds used as pesticides or PVC stabilizers (fenbutatin oxide, triphenyltin chloride, tricyclohexyltin hydroxide, di-n-butyltin dichloride and diphenyltin dichloride) were baseline resolved on a cyanopropyl column (A = 430nm, ex 495nm, em) using a 96/2/2 hexane/THF/acetic acid mobile phase [809]. Detection limits of 1-2 ng injected for standards, 20-30 ng/L for surface water, and 200-300 ng/g for soils were obtained when a postcolumn irradiation/morin (3,5,7,2, 4 -pentahydroxyflavone) reaction was used. 

Sensors for metal ions are based on the use of non-fluorescent or weakly fluorescent reagents which form highly fluorescent complexes with the metal ions of interest. For example, the reagent morin (3, 5, 7, 2 4 -pentahydroxyflavone), immobilized on cellulose by covalent bonding, forms intense fluorescent complexes with aluminium (64) and beryllium (65) which are used to sense these ions. The detection limits for these transducers are reported to be 27 ppb for aluminium and 9 ppb for beryllium. 

Yu, Z., Fong, W.P., Cheng, C.H.K. Morin (3,5,7,2, 4 -Pentahydroxyflavone) exhibits potent inhibitory actions on urate transport by the human urate anion transporter (hURATl) expressed in human embryonic kidney cells. Drug Metab. Dispos. 35(6), 981-986 (2007)... 

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