Pentaerythritol mononitrate

Pentaerythritol Mononitrate (Tris[tris(di. fluoramjnolmethyl ether], FA-PEMON).,... 

Figure 4. Scheme of pentaerythritol tetranitrate degradation - The degradation continued via pentaerythritol mononitrate to pentaerythritol, which might be utilized as a carbon source. 

Pentaerythritol Mononitrate [2,2-Bis(hydroxymethyl)- ,3-propanediol 1-mononitrate (name preferred by CA), PEMNJ. CsHnNOg, mw 181.15, N 7.73%, crysts from chlf, mp 79° (Ref 2), CA Registry No 1607-00-7... 

Glyceryl trinitrate was converted by rabbits to the mono-and 1,3-dinitrate derivatives, which were excreted in the urine. The isomeric 1,2-glyceryl dinitrate was not detected as a metabolite of glyceryl trinitrate. After the administration of 1,2-glyceryl dinitrate, only glyceryl mononitrate (isomeric position unknown) was detected. The metabolism of penta-erythritol trinitrate (IV), an active metabolite of pentaerythritol tetra-nitrate, was studied in dogs. The major metabolites in the urine were pentaerythritol mononitrate and pentaerythritol only the latter compound was present in the feces. An oral dose of pentaerythritol was excreted unchanged by the dog. ... 

Marans and Preckel " synthesized both the mononitrate (95) and the dinitrate (92) esters of metriol by using a similar strategy to that used for pentaerythritol trinitrate. Thus, nitration of both the mono- (90) and the di- (93) acetate esters of metriol, followed by selective hydrolysis of the acetate groups, yields (92) and (95) respectively the latter could be useful as a monomer for the synthesis of energetic polyurethane polymers. 

Simultaneous isosorbide dinitrate, isosorbide mononitrate, pentaerythritol tetranitrate, saccharin... 

Yu, W.C. Goff, E.U. Determination of vasodilators and their metabolites in plasma by liquid chromatography with a nitrosyl-specific detector. Anal.Chem., 1983,55,29-32 [TEAdetection plasma SPE extracted isosorbide dinitrate, isosorbide mononitrate, pentaerythritol tetranitrate LOD 0.1 ng]... 

Pentaerythritol (pe) tetra-nitrate, antianglnal. Rat denitrated, forming PE (m), PE-dinitrate (m), PE-mononitrate (t), in urine and feces. 

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