Penicillium charlesii

Polysaccharides Synthesized by Micro-organisms. I. The Molecular Structure of Mannocaralose Produced from Glucose by Penicillium charlesii G. Smith, W. N. Haworth, H. Raistrick, and M. Stacey, Biochem. J., 29 (1935) 612- 621. 

In this connection there should also be mentioned the formation of carlic acid (XC) from LXXXIX (formed from D-glucose as a metabolic product of the mold Penicillium charlesii G. Smith47). 

Dimethyl-D-mannose has been isolated from the hydrolysis products of the methylated galactomannans from carob seed gum14-18 and from guar gum,16 17 and also from mannocarolose,8t 18 a polysaccharide synthesized by Penicillium charlesii G. Smith. The synthesis of this sugar, which has not been obtained crystalline, has been accom-... 

Absorption Spectra of the Metabolic Acids of Penicillium charlesii and Their Relationship to the Absorption Spectrum of Ascorbic Acid, R. W. Herbert and E. L. Hirst, Biochem. /., 29, 1881 (1935). 

Gliocladium deliquescens Gliocladium virens Macrophomina phaseolina Nodulisporium hinnuleum Penicillium charlesii Periconia circinata Streptomyces sp. 

Methylated fragment Bakers yeast Yeast invertase S accharomyces rouxii Penicillium charlesii Candida albicans Serotype A Serotype B Trichosporon aculeatum ... 

Biosynthesis of carolic acid in Penicillium charlesii, J.L. Bloomer, F.E. Kappler and G.N. Pandey, Chem. Commun., 1972, 242. 

Studies on the biosynthesis of complex glycoproteins such as the ethanolamine/N,N -dimethylaminoethanol-containing peptidophos-phogala tomannan of Penicillium charlesii are limited. Uridine 5 (a-D-galactofuranosyl pyrophosphate) was isolated from extracts of charlesii and tentatively characterized by Trejo al. 

Figure 1. Time course of o-glucose and uptake from the growth medium and increase in dry weight of mycelia of P. charlesii cultures, Penicillium charlesii was cultured in a modified Raulin-Thom medium (24). The contents of the flasks were removed at intervals, filtered and the filtrate was assayed for (O—O) total carbohydrate, (A—A) dry weight, and (A—A) pPGM (23). The initial concentrations...

The present proposal is different and takes into account assignments attributed to a 3-D-(l 5)-linked galactofuranose tetra-saccharide from Penicillium charlesii galactomannan, which was based in turn of assignments for methyl 3-Q-galactofuranoside and its 5-0 -methyl derivative with its attendant a- and 3-shifts... 

Product of metabolism of Penicillium Charlesii, G. Smith. Needles from CgH. M.p. 181°. 

Pepsin inhibitor from roundworms (Ascaris lumbricoides) Peptidophosphogalactomannan(from Penicillium charlesii)... 

A peptidophosphogalactomannan (from Penicillium charlesii) immobilized by reaction with agarose cyclic imidocarbonate has been used as the affinity matrix in the purification of (exo-)p-D-galactofuranosidase. ... 

The biosynthesis of the fungal tetronic acid carolic acid (76 a) in Penicillium charlesii is markedly different from that of patulin, multicolic acid and penicillic acid. Carbon-14 work has demonstrated that the carbon sub-unit C-3, C-4, C-9 in the acid is derived from a C-4-dicarboxylic acid such as succinate, whereas the remaining six carbons (C-1, C-2, C-5, C-6, C-7, C-8) are derived from two malonate units (C-5, C-6, C-7, C-8) and just one acetate unit (C-1, C-2) (Scheme 19) (775). It is proposed then that the biosynthesis of carolic acid proceeds from a C4-dicarboxylic acid first to either y-carboxymethyltetronic acid (196) or to carlosic acid (77 b) hydroxylation of carlosic acid then gives rise to carlic acid (77 a) which on decarboxylation produces carolic acid 176). 

Bentley, R., D. S. Bhate, and J. G. Keil Tetronic Acid Biosynthesis in Molds 1. The Formation of Carlosic and Carolic Acids in Penicillium charlesii. J. Biol. Chem. 237, 859 (1962). 

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