PEG-modified polyurethanes

Li D, Chen H, Gleim McClung W, Brash JL. Lysine-PEG-modified polyurethane as a fibrinolytic surface effect of PEG chain length on protein interactions, platelet interactions and clot lysis. Acta Biomater 2009 5 1864-71. 

Chen X, Liu W, Zhao Y, et al. Preparation and characterization of PEG-modified polyurethane pressure-sensitive adhesives for transdermal drug delivery. Drug Dev Ind Pharm June 2009 35(6) 704-l 1. 

Because the polymer surface reorients the hydrophilic groups toward polymer/water interfaces, modified polyurethanes show much lower CA after hydration (Table 2.1). PU-PEG IK-OH, PU-PEG IK-NH2, and PU-PEG IK-SO3H show complete wetting (undetectable 6(ec) after hydration, suggesting a superhydrophilic nature of the modified surfaces. The hydrophilic surface modifications greatly reduced Escherichia coli adhesion. 

If toughness is not the limiting consideration, then the simple addition of PEG soft segment appears to offer an attractive route to the production of polyurethanes with 25 to 30 wt.% lignin. It is important to note that both of the studies considered here have employed modified lignins. The relative advantage of hydroxypropylation (16) over fractionation (19) would depend on the relative cost of either procedure. 

Castor oil-based polyurethanes have ten times more lap shear strength than commercially available wood adhesives. Castor oil-based polyurethanes are widely used as adhesives in the biomedical and other fields. Castor oil-based polyurethane is also reported to be biocompatible and has been used successfully as a material for making artificial bone. Polyurethanes based on a castor oil-modified polyol and a PEG chain extender... 

The MBEC assay described is designed for antibiotics rather than polyurethane materials. Therefore, Russell et al. [191] modified this method to evaluate acrylate-urethane coating s performance. Salicylic acid was first conjugated with an acrylate group to form a polymerizable monomer. This monomer was then copolymerized with urethane acrylate via UV free radical polymerization (Figure 2.36). The peg cones on... 

Polyurethane foam synthesis can be modified by additions of PEG in such a way that an open-cell, very flexible, highly elastic foam is produced, for example, for upholstery. 

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