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Peg-filgrastim

Be aware of signs and symptoms of allergic reactions that may occur with peg-filgrastim... [Pg.945]

PEG-G-CSF PEG-filgrastim, Neulasta 2002 Prevention of neutropenia associated with cancer chemotherapy 30... [Pg.1368]

PEG-grannlocyte-colony stimnlating factor (G-CSF) PEG- filgrastim, Nenlasta Prevention of chemotherapy-associated neutropenia 2002 [55]... [Pg.236]

Lord, B.I., L.B. Woolford, and G. MoUneux, Kinetics of neutrophil production in normal and neutropenic animals during the response to filgrastim (r-metHu G-CSF) or filgrastim SD/01 (PEG-r-metHu G-CSF). Clin Cancer Res, 2001. 7(7) 2085-90. [Pg.136]

Fig. 15.1 Structure of pegfilgrastim. A relatively compact protein (filgrastim) is shown at the top of this molecule model. Despite having a similar molecular weight to filgrastim (18.8 kDa), the PEG moiety (20 kDa), shown at the bottom, is loosely hydrated and occupies a relatively large volume. (Adapted with permission from [12]). Fig. 15.1 Structure of pegfilgrastim. A relatively compact protein (filgrastim) is shown at the top of this molecule model. Despite having a similar molecular weight to filgrastim (18.8 kDa), the PEG moiety (20 kDa), shown at the bottom, is loosely hydrated and occupies a relatively large volume. (Adapted with permission from [12]).
Chapter 3) produced by recombinant means in E. coli. It regulates the production of neutrophils and is indicated for the treatment of neutropenia associated with various medical conditions. Neulasta is a PEGylated form filgrastim, also used to treat neutropenia. It exhibits an extended duration of action, due to the PEG-mediated reduction in product renal clearance rate. [Pg.32]

See other pages where Peg-filgrastim is mentioned: [Pg.1470]    [Pg.73]    [Pg.508]    [Pg.306]    [Pg.452]    [Pg.1470]    [Pg.73]    [Pg.508]    [Pg.306]    [Pg.452]    [Pg.213]    [Pg.249]    [Pg.159]    [Pg.370]    [Pg.249]    [Pg.4]    [Pg.27]    [Pg.376]    [Pg.376]    [Pg.266]    [Pg.1542]    [Pg.345]    [Pg.1014]    [Pg.1406]    [Pg.1411]    [Pg.249]    [Pg.776]    [Pg.132]    [Pg.307]    [Pg.760]    [Pg.238]    [Pg.826]    [Pg.15]    [Pg.353]    [Pg.34]   


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Filgrastim

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