PCNA proliferating cell nuclear

PCA Passive cutaneous anaphylaxis pCDM8 Eukaryotic expression vector PCNA Proliferating cell nuclear antigen... [Pg.285]

PCNA, proliferating cell nuclear antigen HE, hematoxylin and eosin. [Pg.28]

One fascinating observation is that PCNA (proliferating cell nuclear antigen) can be modified by multiple forms of ubiquitin, demonstrating that DUBs with different specificities can act at the same location on a specific substrate. PCNA can be modified by mono-ubiquitin, 63-linked polyubiquitin, or SUMO at K164 [89]. Modification of PCNA by mono- or polyubiquitin determines whether it is utilized in translesion synthesis or error-free DNA repair, respectively. SUMO modification prevents PCNA function in DNA repair and instead promotes DNA replication. It is probable that multiple DUBs, as yet unidentified, are required to regulate PCNA modification. [Pg.205]

PCNA—Proliferating cell nuclear antigen Breast carcinoma also in other epithelial tumors... [Pg.55]

PCNA proliferating cell nuclear antigen TSH thyroid stimulating hormone... [Pg.577]

The primer is extended into daughter-strand DNA by DNA polymerase 8 (Pol 8), which is less likely to make errors during copying of the template strand than is Pol a. Pol 8 forms a complex with Rfc (replication factor C) and PCNA (proliferating cell nuclear antigen), which displaces... [Pg.134]

PARP, mono/polyADP (adenosine diphosphate) libose polymerase. Binds PCNA (proliferating cell nuclear antigen) for translesion DNA repair/synthesis. Click for... [Pg.223]

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