Pathway Resource List

Pathguide http //www.pathguide.org/ The pathway resource list... 

Bader GD, Cary MP, Sander C. Pathguide A pathway resource list., Nucleic Acids Res. 2006 34(Database issue) D504-D506. 

The World Wide Web Virtual Library Biosciences points to virtual library pages for Biological Molecules, and Biochemistry and Molecular Biology. Each of these pages presents a long list of Web resources. The World Wide Web Virtual Library Biological Molecules covers molecular sequence and structure databases, metabolic pathway databases, and other lists of Web resources. The World Wide Web Virtual library Biochemistry and Molecular Biology is a list of resources, listed by provider. 

What is required is a form of resource and technology assessment. This could be summarized in a matrix in which the potential of each resource and technology can be quantified and charted. This matrix is shown in figure 2 the items in each column are illustrative and the lists are by no means exhaustive. The identification of R D requirements then requires a techno-economic assessment of the possibility of different pathways through the matrix, and is the product of (Resource) (Transport) (Conversion Technology) (Transport) (End Use). 

The primary metabolic information can also be obtained from PathDB of National Center for Genome Resources (NCGR) at http //www.ncgr.org/software/ pathdb/. Click Simple Web Query to open the query page. Choose Pathway/Step/ Catalyst or Compound from the Retrieve pop-up list (search by compound is the... 

Metabolism includes all of the chemical transformations that occur in living systems. A detailed discussion of metabolism is beyond the scope of this chapter and the reader is directed to other comprehensive resources (22). The lesson to impart to all students interested in green chemical design is that fundamental chemical reactions are the foundation of all of biotransformation. Addition reactions, conjugation reactions, substitutions and eliminations occur to chemicals found naturally inside living systems (biochemistry) and to those that are found external to living systems (xenobiotics) as well as in laboratory round-bottom flasks. Table III lists some of the more common biotransformation pathways. 

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