Pathophysiological role

Miller RJ, Banisadr G, Bhattacharyya BJ (2008) CXCR4 signaUng in the regulation of stem ceU migration and development. J Neuroimmunol 198 31-38 Minami M, Satoh M (2003) Chemokines and their receptors in the brain pathophysiological roles in ischemic brain injury. Life Sci 74 321-327... 

Z4. Zenichi, M., Masakazu, U., Koichi, A., Masao, E., and Masaki, K Pathophysiologic role of en-dothelin-l in renal function in rats with endotoxin shock. Surgery 115,199-204(1994). 

Tabaqchali S The pathophysiological role of small intestinal bacterial flora. Scand J Gastroenterol Suppl 1970 6 139-163. 

In addition, there is now good evidence indicating that methyldopa effectively suppresses the release of renin by the kidney(23,24). This effect may contribute to the antihypertensive efficacy of the drug in some hypertensive states in which the renin-angiotensin system plays a pathophysiologic role. Thus, it may be concluded that a) methyldopa lowers the blood pressure... 

The pathophysiological role of oxidized LDL-induced apoptosis in vessel wall homeostasis is complex and probably depends on the cell type that oxLDL interacts with. For instance, EC are potential early targets, oxidized LDL may alter their functions and lead to apoptosis, contributing to early... 

Igarashi, Y. and Yatomi, Y., 1998, Sphingosine 1-phosphate is a blood constituent released from activated platelets, possible playing a variety of physiological and pathophysiological roles. Acta Biochim. Pol. 45 299-309. 

In addition to ions, other small molecules have been described to play an important physiological and pathophysiological role in the regulation of gap junctional resistance. Thus, ATP acts as an important regulator. In 1979 Wojtcak described that hypoxia in glucose free solution resulted in a rise in Rj in cow ventricular trabeculae indicating that the intracellular ATP content... 

Analysis of BAs in urine, serum, bile and stool is crucial for the diagnosis of inborn errors of BA metabolism. It is also helpful for understanding their pathophysiological role in acquired hepatic diseases and for monitoring the effects of therapy on metabolism. Several different inborn defects affecting BA synthetic pathway, have been described over last 20 years [7]. 

Quartara, L. and Maggi, C.A. The tachykinin NK1 receptor Part II. Distribution and pathophysiological roles, Neuropeptides 1998, 32, 1-49. 

Abbracchio MP, Bumstock G (1998) Purinergic signalling pathophysiological roles. Jpn J Pharmacol 78(2) 113-145... 

Adams KF, Jr. Pathophysiologic role of the renin-angiotensin-aldosterone and sympathetic nervous systems in heart failure. Am J Health Syst Pharm. 2004 61(suppl 2) S4-S13. 

The physiological and pathophysiological role of presynaptic orexin receptors is incompletely understood, and drugs targeting orexin receptors so far have not been developed. Orexins play an important role in the control of sleep and wakefulness, as highlighted by the findings that the knockout of preproorexin in mice (Chemelli... 

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