Paternally Transmitted Teratogenic Effects

Teratogenic effects can result from paternal as well as maternal exposures to toxic chemicals.I6,7 Table 24.2 lists paternal occupations that have been associated with birth defects in offspring. El 

All these occupations have exposures to chemical mixtures associated with them. For most, the specific causative agents are unknown. Examples of paternal exposures leading to teratogenic effects are given in Section 24.5. 

Disinfection byproducts Trihalomethanes Haloacetic acids Haloketones Haloacetonitriles 

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It has been recently established that paternal exposures to teratogenic effects can be transgenerationally transmitted. The following example illustrates this effect. 

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