Patent filing target structure

Abbott compares SAR by NMR to combinatorial chemistry as follows Both methods use a building block approach in the construction of molecules however, in combinatorial chemistry, thousands to millions of molecules are typically synthesized and tested for activity. In SAR by NMR, less than 10 molecules is required because the chemistry is highly focused on linking molecules demonstrated to bind to the protein target using structural information on how they interact. Patent applications have been filed on the method, but the company plans to make the technology available to other drug developers. 

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