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Particle film-coating

Iley, W.J. Effect of particle size and porosity on particle film coatings. Powder Technology 65(1-3) (1991) 441- 5. [Pg.34]

In liquid-liquid chromatography the stationary phase is a liquid film coated on a packing material consisting of 3-10 pm porous silica particles. The stationary phase may be partially soluble in the mobile phase, causing it to bleed from the column... [Pg.579]

A widely used method to produce multiple-unit dosage forms has been the production of sachets that contain film-coated granules. More common is the use of capsules in which enteric-coated particles are filled. A study that used radioactive tracers revealed that enteric-coated erythromycin pellets in capsules were superior to enteric-coated tablets with respect to faster action of the drug caused by a shorter passage time of the coated granules in the stomach [49-51],... [Pg.25]

Table 3 Elongation at Break of Different Film Coatings, Measured According to ISO 527. High Values of the Elongation at Break Are Indicators for Flexible Film Coatings. Flexible Enteric Films are Required for the Compression of Enteric-coated Particles... Table 3 Elongation at Break of Different Film Coatings, Measured According to ISO 527. High Values of the Elongation at Break Are Indicators for Flexible Film Coatings. Flexible Enteric Films are Required for the Compression of Enteric-coated Particles...
CGP 57813 is a peptidomimetic inhibitor of human HIV-1 protease. This lipophilic compound has been successfully entrapped in polylactic acid (PLA) and into pH-sensitive methacrylic acid copolymer particles (EUDRAGIT L 1 GO-55) [69], After the application of a film-coating, the plasma concentration was acceptable and reached similar levels as with injections of drug-loaded PLA carriers. To hinder the proteolytic degradation of a drug, two types of enteric-coated pellets were applied simultaneously. One contained the protease inhibitor coated... [Pg.32]

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See also in sourсe #XX -- [ Pg.189 , Pg.215 ]



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